What would result in the presence of spherocytes on the peripheral blood smear?  What about schistocytes?
<answer>
Spherocytes are present in patients with <span style="text-decoration:underline;"><strong>hereditary spherocytosis</strong></span> or <span style="text-decoration:underline;"><strong>immune-mediated hemolysis.</strong></span> 

The presence of schistocytes suggests a <span style="text-decoration:underline;"><strong>microangiopathic hemolytic anemia</strong></span> or <span style="text-decoration:underline;"><strong>mechanical shearing of erythrocytes </strong></span>

(Mayo Clin Proc, Vol. 84, pg. 281).
</answer>

Name the 4 metabolic derangements associated with the Tumor Lysis Syndrome.
<answer>
Hyperuricemia 
Hyperphosphatemia 
Hyperkalemia 
Hypocalcemia 

(Mayo Clin Proc, Vol. 81, pg. 838).
</answer>

What is the significance of the presence of schistocytes on a peripheral blood smear?
The presence of schistocytes on a peripheral blood smear would suggest a <span style="text-decoration:underline;"><strong>microangiopathic hemolytic anemia </strong></span>or <strong><span style="text-decoration:underline;">mechanical shearing of erythrocytes
</span></strong> 
(Mayo Clin Proc, Vol. 84, pg. 281).