Anatomy the study of structure of the body Four ways to study Anatomy Inspection (physical exam) , Dissection (cadaver vs. comparative anatomy), Gross Anatomy (naked eye), Microscopic Anatomy (microscope) Palpation Touch auscultation Listen percussion tap Physiology the study of the function of the body Organism individual living thing Organ System group of organs that work together for a specific task Organ group of two or more tissue types with a specific function Tissue a group of similar cells that form a region of an organ & have similar structure and function Cell smallest unit of a living organism that can carry out the basic functions of life Organelle differentiated structure within a cell Molecule particle made up of at least two atoms Atom smallest particle matter with an unique chemical identity Homeostasis maintaining a constant internal environment or equilibrium stress any disruption of homeostasis that threatens physical or emotional well-being Negative Feedback process where the body senses a change and activates mechanism to negate or reverse it components of negative feedback receptor or sensor(senses the change), integrating or control center (process the information from the receptor and make a "decision" on how to respond), effector (cell or organ that carries out the corrective action) Positive feedback a self-amplifying cycle in which a physiological change leads to even more change in the same direction Integumentary System skin, hair, nails. Function: protection, thermo regulation, vitamin D Skeletal System bones, cartilage, ligaments. Function: support, protection, movement, blood cell formation Muscular System skeletal muscles. Function: movement, stability Nervous System nerves, brain, spinal cord, ganglia. Function: communication, coordination, motor control, sensation. Endocrine System pituitary, pineal, thyroid, parathyroid, thymus, adrenals, pancreas, testes, ovaries. Function: hormones Cardiovascular System heart, blood vessels. Function: distribute nutrients, oxygen, hormones, waste, etc. Fluid balance. Lymphatic System lymph nodes, lymph vessels, thymus, spleen, tonsils. Function: defend against disease and recovery of excess tissue fluid. Respiratory System nose, pharynx, larynx, trachea, bronchi, lungs. Function: absorb oxygen, discharge CO2, acid-base balance, speech. Digestive System mouth, pharynx, esophagus, stomach, SI, LI, liver, gallbladder, pancreas. Function: nutrient breakdown and absorption. Urinary System kidneys, ureters, urinary bladder, urethra. Function: elimination of waste, regular blood pressure and blood volume, stimulate red blood cell (RBC) production, electrolyte and acid-base balance Female Reproductive System ovaries, uterine tubes, uterus, vagina, mammary glands. Function: egg production, fetal development, make sex hormones, lactation. Male Reproductive System testes, vas deferens, prostate, penis. Function: sperm production, makes sex hormones. Hypothetico-deductive method: Four Steps: 1. observation. 2. hypothesize 3. experiment 4. conclusions & reporting Inductive Method: make numerous observation to draw generalizations and predictions. raises issue of proof Considerations in experiments Variable (any condition of an experiment), Experimental Group (group that contains the tested variable), Control Group (group that does not contain the tested variable) Matter anything that has mass and takes up space. All organisms are made of matter. Element a substance that cannot be changed into another substance. Ex. Hydrogen, Oxygen. Atom the smallest particle of an element that retains the characteristics of the element. Neutron neutral charge. (in nucleus) Electrons negative charge (orbit around nucleus) Proton positive charge (in nucleus) Atomic number number of proton Atomic mass protons + neutrons Isotope atoms of an element with different numbers of neutrons Molecule particle made of 2 or more atoms united by a chemical bond. diatomic molecule molecule consist of 2 of the same type of atom bonded together compound molecule consist of 2 or more different elements Ions charged atoms with unequal numbers of protons and electrons. They give up or gain an electron to try to become more stable. Cation positively charged ion. gave up an electron Anion negatively charged ion. gained an electron Electrolytes salts that ionize in water and form solutions capable of conducting electricity. = ions Free radical a chemical particle carrying an odd number of electrons. BAD Antioxidant a chemical that neutralized free radicals GOOD Ionic bonds two ions are attracted to each other and bond because of an opposite charge. weak. covalent bonds two atoms share electrons. [strongest bond] Non-polar covalent bond evenly distributing charge Polar covalent bond water. have slight opposite charges on either end Hydrogen bonds water molecules. the - side of the molecule (oxygen) is attracted to the + side of another molecule [hydrogen]. Not stuck together, just stay close. weakest Acid a compound that releases hydrogen ions in solution Base a compound that accept hydrogen ions Salt an ionic compound that does NOT contain H+ or OH- and comes from an acid-base reaction pH the measurement of the H+ concentration in a solution. Expression of acidity pH=7 neutral pH pH<7 acidic pH pH>7 Basic or Alkaline pH low pH higher H Normal blood & tissue pH 7.35- 7.45 Buffer any mechanism that resists large changes in pH. maintain homeostasis for pH. Chemical buffers take up or give off H+ ions Physiological buffers control output of acids, bases, or CO2. 3 Chemical Buffers 1. Bicarbonate: Shift to the right, equals more Hydrogen in body which makes pH lower. Shift to left decreases Hydrogen ions, which increases pH. 2. Phosphate: Proteins: 2 Physiological Buffers 1. Respiratory system: 2-3 times stronger than chemical buffers. breath CO2. ventilation less or more adds or decreases CO2. 2. Urinary System: Because it actually expels H+ from the body, the urinary system is the strongest buffering system in our body. adhesion tendency of one substance to cling to another cohesion the tendency of molecules of the same substance to cling to each other capillary action the movement of liquid along the surface of a solid due to the attraction of the liquid molecules to the solid molecules surface tension manifestation of cohesion of water at the surface high specific heat the amount of heat needed to raise the temperature of 1 gram of a substance by 1 degree C High heat of vaporization amount of heat it takes to convert liquid to vapor Water Covalently bonded, polar molecule. Solvency ability to dissolve other chemicals. Chemical reactivity ability to participate in chemical reactions. Organic chemistry the study of carbon compounds Four types of organic molecules: Carbohydrates, Lipids, Proteins, Nucleic Acid. monomer or subunit of carbohydrated monosaccharides (aka simple sugars) ex. glucose, fructose Functions: source of energy and in structure Lipids: Monomers: fatty acids and alcohols. Functions: energy storage. thermal insulation. cushion. cell membrane structure. chemical signals between cells Proteins. Monomer: amino acids. functions: structure: Keratin (hair, skin, nails). Collagen (cartilage, deep layers of skin) communication: hormones Membrane transport Metabolism: enzymes Protection: antibodies, clotting proteins Nucleic Acids:monomer: nucleotides example: DNA, RNA functions: heredity, protein synthesis ATP Adenosine Triphosphate. a nucleotide. The fuel of living cells. Dehydration Synthesis assembling organic molecules by extracting water. aka condensation. Hydrolysis breaking up organic molecules using water. Proteins that function as biological catalysts lower the activation energy [energy needed to start a reaction], speeding up chemical processes Enzymes are: ubstrate {substance the enzymes act on} specific not consumed by the reaction they catalyze affected by pH and temperature outside of the ideal range which change their shape. must be in perfect condition to work pH and temperature outside of the ideal range can change the shape of an enzyme (disrupts hydrogen bonds) [[ enzymes must be in perfect shape and condition to work]]