What plane divides the mediastinum into superior / inferior parts? Transverse thoracic plane (T4/5 IV disc) Inferior mediastinum subdivided (anterior / middle / posterior) Supine position of mediastinum aortic arch superior to TTP (T4/5 IV disc) tracheal bifurcation transected by TTP central tendon lies at xiphisternal junction (T9) Standing position of mediastinum aortic arch transected by TTP (T4/5 IV disc) central tendon may fall to xiphoid process (T9/10 IV disc) Contents of superior mediastinum (anterior to posterior) Thymus SVC Brachiocephalic vv. Aortic arch (BCT / LCC / LScl) Vagus / Phrenic nn. Cardiac nerve plexus L. Recurrent Laryngeal n. Trachea Esophagus Thoracic duct Prevertebral mm. Contents of anterior mediastinum Remnants of thymus Lymph nodes Fat & CT Contents of middle mediastinum Pericardium Phrenic nn. Heart / cardiac plexus Roots of great vessels Azygos arch Main bronchi Tracheobronchial lymph nodes Contents of posterior mediastinum Thoracic aorta Thoracic duct Tracheobronchal LN Azygos / Hemiazygos vv. Esophagus Esophageal plexus Sympathetic trunks Splanchnic nn. Vagus nn. What structures pass w/in space between pericardial sac and visceral pleura? Pericardiacophrenic aa. Pericardiacophrenic nn. Phrenic n. Organization of Pericardium Outer layer = fibrous pericardium Inner layers = serous pericardium (double layer visceral & parietal) Where does the transverse pericardial sinus lie? Anterior to SVC Posterior to Aorta & Pulmonary Trunk Continuous from left to right sides of heart (oblique pericardial sinus = blind pouch) Pericardial Vasculature Pericardiacophrenic a. (branch of int. thoracic a.) Pericardiacophrenic vv. (dumps into brachiocephalic vv.) Innervation of Pericardium Phrenic n. (C3-C5) Somatic only Relationship of structures in middle mediastinum phrenic n. passes anterior to root of lung vagus n. passes posterior to root of lung pericardiacophrenic vessels & phrenic n. superficial to fibrous pericardium Fibrous skeleton of heart 4 annuli fibrosi (fibrous rings) fuse together CT skeleton separates musculature of atria from ventricles (attachment for valves / myocardial fiber bundles) Innervation of Heart Sympathetics - postganglionic fibers (cervical ganglia) -> cardiac plexus - adrenergic (norepinephrine; increase HR / force) - visceral afferents carry pain Parasympathetics - vagus n. - cholinergic (ACh; decrease HR / force / constrict BV) Where is the SA node located? junction of SVC & superior crista terminalis Where is the AV node located? posteroinferior region of interatrial septum (near orifice of coronary sinus) Where do the branches of the AV node divide? junction of membranous / muscular parts of interatrial septum CORONARIES CORONARIES Venous drainage of Heart VENOUS Lymphatic drainage of Heart lymphatics form network adjacent to endo/epicardium efferent vessels drain along coronary aa. empty into tracheobronchial nodes (lower end of trachea) What is the function of the thymus? Produces lymphocytes Gradually degrades post-puberty (replaced by fat) Blood supply to the thymus Internal thoracic aa. Superior thyroid aa. Lymphatic drainage of the body 3/4 = thoracic duct (left) 1/4 = r. lymphatic duct Brachiocephalic veins Formed by subclavian / internal jugular vv. L. BCV is 2x longer than R. BCV R/L BCV unite to form SVC (1st costal cartilage) R. Brachiocephalic v. receives lymph from... R. Lymphatic Duct (1/4) L. Brachiocephalic v. receives lymph from... Thoracic Duct (3/4) Brachiocephalic Trunk Most anterior branch of aortic arch - Posterior to L. BCV - Anterior to trachea Divides into RCC / RScl Left Common Carotid Artery Middle branch of aortic arch Ascends post. to left sternoclavicular joint (into neck) Left Subclavian Artery Most posterior branch of aortic arch Ascends lateral to trachea Where do the phrenic nn. lie as they run into thorax? Lie on anterior surface of anterior scalene mm. Where do the vagus nn. lie as they run into thorax? Lies deep to carotid sheath b/w common carotid aa. & internal jugular vv. in neck Path of R. recurrent laryngeal n. branches from r. vagus n. (anteromedial to RScl a.) wraps posteriorly around RScl a. ascends in tracheoesophageal groove innervates all intrinsic muscles of larynx except cricothyroid m. Path of L. recurrent laryngeal n. branches from l. vagus n. (anteromedial to aortic arch) wraps around aortic arch (posterolateral to ligamentum arteriosum) ascends similar to r. recurrent laryngeal Origin of superior phrenic aa. Inferior part of thoracic aorta Esophageal nerve plexus Anterior vagal trunk arises from L. vagus n. Posterior vagal trunk arises form R. vagus n. "hang a right" Innervation to esophagus Vagus n. (motor / secretomotor / sensory) Sympathetics (vasomotor) Superior esophagus - recurrent laryngeal nn. - sympathetics (middle cervical ganglion) Inferior esophagus - esophageal plexus - parasympathetics (vagus nn.) - sympathetics (gray rami upper 4 thoracic ganglion) Main blood supply to esophagus Esophageal branches of thoracic aorta Thoracic duct Begins at cisterna chili Empties on left side at junction of internal jugular / L. subclavian vv.