Give general information about Myelodysplastic Syndromes? (characterized by? age affected? presentation?)
Diverse group of closely related disorders
Characterized by ineffective hematopoiesis, neoplastic clonal stem cell proliferations
Affect persons 60+
Presentation often similar to leukemia
Varies in presentation and course

What are myeloproliferative disorders? What specific disorders are included?
Acquired malignant clonal proliferations of stem cells
idiopathic myelofibrosis
Polycythemia vera
Essential primary thrombocythemia

Give general information about Plasma Cell disorders. (characterized by? Age? Etiology?)
Plasma cells are normally 1.5% of nucleated marrow cells
Proliferation of plasma cells and/or plasmacytoid lymphocytes (associated with monoclonal production of Ig)
Polyclonal increases are reactive
Occurs after the age of 40
Etiology unknown
Types include Multiple myeloma and Waldenstroms macroglobulinemia

Information about Lymphomas (definition? Etiology?)
Solid tumor with a proliferation of one of more types of cells from the lymphoid series
Initially develops in areas such as marrow, spleen, or lymph nodes
Can disseminate into blood
Unknown etiology (same things that cause leukemias)