Dose of drugs
Pethidine + Phenargan - 50mg+25mg IM sos
Ketorolac 30mg IV tds
Calcium dobesilate for varicose vein
Tab cefadroxil 500mg BD
Inj Phenytoin 100mg TDS
Tab Cotrim DS 1 tab po BD
Inj Octreotide 100micro gram sc TDS
10% calcium gluconate, 10ml over 10 minutes
Inj UFH 5000 IU SC BD
Tab Strocit (Citicholine) 500mg PO BD
Tab Stemetil (Prochloroperazone) 5mg IV sos
Inj Rallidex NS (Dextran 40) - for hypovolemic shock/ septic shock/severe burns
Seranace - haloperidol
Laxopeg - laxative + PEG
Inj Granisatron 1mg IV OD
Inj MgSO4, 1gm in 100ml NS IV over 4 hours
Pain management
Tab TRD contin 1 tab PO BD
Morphine 3mg TDS
Durogesic (Fentanyl transdermal patch) Local application for pain management
Syp Mor 5ml (2mg/ml) SOS
Tab Morcontin 10mg PO sos
Supportive medicines and total parenteral nutrition
Pentasure + Soyaprotein 2tsf each in a glass of milk TDS
Triptene buscits 2piece BD
Inj Alanine I unit IV BD
Inj Celemin (amino acids + sorbitol) I pint IV BD
Inj Celepid (intravenous fat) I pint IV OD
Inj Oliclinomol 1 litres IV over 16 hours and 8 hours gap
Use 10% dextrose in between the TPN to prevent hypoglycemia. TPN is given for 16 hours, and then 10% dextrose in eight hours
Urinary system
Tab flavoxate 200mg PO TDS - anticholinergic, indicated for symptomatic relief of interstitial cystitis, dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis
Oxyspas (Oxybutynin) 2.5/5mg - anticholinergic- to treat overactive bladder
Tab Urimax (Tamsulosin) 0.4mg PO HS - alpha 1 adrenergic blocker
Tab Alfuzosin 10mg PO OD - alpha 1 adrenergic blocker
GI system drugs
Itopride (Ganaton, Gantoon) 50mg PO TDS. It is a prokinetic benzamide derivative unlike metoclopramide or domperidone. It is used in dyspepsia of a non-ulcer/dysmotility type (gastric "fullness", discomfort, and possible pain), delayed gastric emptying and anorexia
For ulcerative colitis
Mesacol (Meselamine) 400mg PO TDS - 1 hr before food or 2 hours after food
Respiratory system drugs
Seroflo rotacap - Contain salmeterol + Fluticasone
Tiova - Tiotropium
Nacfil (N acetylcysteine) 600mg PO tds as mucolytic agent
Cardiovascular system
Inj Amiodarone 900mg in 500ml NS over 24 hours. (amiodarone in 150mg/3ml injection)
Amiodarone
- 1ml = 50mg, 1ampoule = 150mg
- How to prepare - 7ampoules (1050mg in 50ml (21ml drug + 29ml 5% dextrose)
- Bolus dose - 150mg over 10 minutes jQuery110101646906235989285_1485174722241jQuery110104313412200343545_1498016749827?
GTN 30microgram/kg/min
Labetalol - bolus 2.5mg IV stat
Tab Diazepam (NOTEN) 2mg PO BD
Endocrine system
Zoledronic acid 5mg/100ml IV infusion - is a biphosphonate used in Bone complications of cancer, osteoporosis and paget's disease
Neuro drugs
Tab Pregabalin 75mg PO BD
Diamox (acetazolamide) 250mg TDS
Immunosupresents -
Immunosupressents in Renal Transplant
- Tab Pangraf (tacrolimus) 2.5mg PO BD
- Tab Mycofit (Mycophenolate) 1gm PO BD
- Tab Cortilone 20mg PO OD
Anti-thymocyte globulin (ATG) 60mg in 500ml of NS - is an infusion of horse or rabbit-derived antibodies against human T cells, which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia.
Blood disease
Neupogen (filgrastim) 0.5ml sc stat - is a granulocyte colony-stimulating factor (G-CSF) analog, used to stimulate the proliferation and differentiation ofgranulocytes
Acitrom (Acenocoumarol) 2mg
Enoxaparin (LMWX) 60mg SC
ATT drugs dose
HRZES 5, 10, 25, 15, 15 mg/kg/day
Triple drug regimen in IV
Inj Pantocid 40mg IV BD
Inj Clavum 1.2gm IV BD
Inj Levoflox 500mg IV BD
Oral hypoglycemic drugs
Tab Glycazide 5mg PO BD continue (for mild renal failure, upto grade III CKD)
Insulin
Fast acting
- regular insuin (Huminsulin, Soluble insulin, actrapid)
- insulin lispro (Humalog)
- Insulin aspart (Novorapid)
Intermediate acting - NPH (Isophane, Insulatard)
Long acting
- Glargine (Lantus) -
What is Mixtard?
Mixtard contains both fast-acting (soluble) and long-acting (isophane) insulin:
Mixtard 30: soluble insulin 30% and isophane insulin 70%;
Mixtard 40: soluble insulin 40% and isophane insulin 60%;
Mixtard 50: soluble insulin 50% and isophane insulin 50%.
Novomix 30 -
- Soluble insulin aspart (rapidly-acting insulin, within 10 to 20 minutes)
- Protamine-crystallised insulin aspart (intermediate-acting insulin) - It takes longer to act, but its effects last much longer.
Cardiovascular system
Tab TGR (Fenofibrate) 160mg OD for 3 months - to reduce cholesterol and triglyceride
Renal system drugs
Desmopressin (Minirin) 2 puff stat and repeat
Inj Vasopressin 2U s/c stat
If Urine output is >1000ml/hr, 500ml in two consecutive hour or >300ml in three consecutive hours
Tab Fludrocortisone 200mg PO BD
What is nupogen?
Neupogen is used to stimulate the production of granulocytes (a type of white blood cell) in patients undergoing therapy that will cause low white blood cell counts
Broad spectrum coverage
Inj Tazopip 4.5 gm iv TDS
Inj Clindamycin 600mg iv TDS
What to look for patients on anticoagulants
New spots of bleeding
Intracranial bleeding leading to hypertension
GIK
10U regular insulin with 10mEq/L potassium in 500ml of 10% dextrose at 100ml/hr
Uses in
- Myocardial infarction
- Septic shock
Drug of choice for any bite
Amoxyclave
Antibiotics
Cell wall inhibitors
- Inj Imipenam 500mg +Cilastatin 500mg - 1gm IV TDS or QID (Not more than 4gm/day and >1.5gm/dose)
- Inj Meropenam 1gm IV in 100ml of NS BD
- Vancomycin (500mg in a vial) - 10 mg/kg per dose given every six hours, concentrations of no more than 5 mg/mL and rates of no more than 10 mg/min are recommended in adults.
Inj Acyclovir 800mg IV TDS
- Inj Teicoplanin (Targocid) 400mg IV stat followed by 200mg IV OD. Teicoplanin is
Protein synthesis inhibitor
- Inj Clindamycin 600mg IV tds
- Inj Streptomycin 750mg IM OD
Nucleic acid synthesis inhibitor
- Levofloxacin 750mg OD for hospital acquired pneumonia
Tigecycline and Polymyxin B most strongest antibiotics, very expensive. Polymyxin B is an antibiotic primarily used for resistant Gram-negative infections
Polymyxin B 5 lakhs units diluted in 500ml of 5% dextrose over 1-1.5 hours BD
Inj Tigecycline 100mg IV stat followed by 50mg IV BD
What is Teicoplanin?
Teicoplanin owns a molecular structure which is related to that of vancomycin with similar spectrum of activity. Its mechanism of action is to inhibit peptidoglycan polymerization.
Due to its reduced rate of side effects that does not require close monitoring, its longer serum half-life and a simplified mode or application, teicoplanin is a valuable alternative of Vancomycin and has become the glycopeplide or choice in many hospitals.
What is tigecycline?
This antibiotic is the first clinically available drug in a new class of antibiotics called the glycylcyclines. It is structurally similar to the tetracyclines.
Tigecycline is active against
- Gram-positive bacteria
- Gram-negative bacteria
- Anaerobes
- Methicillin-resistant Staphylococcus aureus (MRSA)
It has no activity against Pseudomonas spp. or Proteus spp.
Alcohol withdrawal
Tab Chlorodiazepoxide 15mg PO BD
Trade names
Magnex Forte - Sulbactam and cefoperazone
Cilanem - Imipenam + Cilasten
Tazobactam
Decreases platelets
Immunosupressant drugs
Tab Tacrolimus 1mg po BD
Tab Mycophenolate 500mg PO BD
Different drugs available at
Cholestyramine sachet in Norvik hospital
Vitamins
Thiamine
Riboflavin - 25, 50mg
Pyridoxine - 10mg tablet
Unit and Pint
Unit - 350 ml
Pint - 500 ml
Pleurodesis
Oxytetracycline (50mg/ml) - 20ml of Oxytetracycline (1gm) in 70ml of NS with 10ml of xylocaine, tetracycline is irritant, so needs lignocaine
Bicarbonate replacement
Number of ampules = (0.3 X base deficit X weight)/9
Ionotropes dose
Dopamine and Dobutamine
- Dopamine - 1ampule - 200mg
- Dobutamine - 1ampule - 250mg
- preparation - body weight X 3 mg in NS/D5
- ml/hr = mcg/kg/min
- Dose - 5-20mch/kg/min
Noradrenaline/Adrenaline
- Noradrenaline - 1ampule - 4mg
- Preparation - 4mg in 50ml of NS/D5
- Dose - 0.01-0.3 mcg/kg/min
GTN
- 1ampule - 25mg
Goals of resiscutitation
SBP > 90mmHg
MAP >65 mmHg
CVP 8-12 mmHg (12-15 mmHg in mechanically ventilated patients)
Urine output - >0.5ml/kg/hr
ScVO2 >70%
Doses of vasopressors
Escalate every 5 minutes
Descelate every 30 minutes
Dopamine and dobutamine
- Preparation - body weight X 3 mg in 50ml NS/D5W
- ml/hr = mcg/kg/min
- Dose - 5-20 mcg/kg/min
- Route - peripheral/central line
Noradranaline and adrenaline
- Preparation - 4mg in 50ml NS/D5W or 8mg in 100ml NS/D5W
- Dose - 0.01-0.3 mcg/kg/min
- Route - central line
Hemorrhoids d
Protek oinment - Lidocaine, Hydrocortisone, Zinc oxide and allantoin