Flumazenil(Romazicon) Class
Benzodiazepin receptor antagonist
Note to self Flumazaenil is to Benzo as Narcan is to Opiod
Flumazenil(Romazicon) MOA
Antagonizes the actions of benzodiazepines on the CNS
Flumazenil(Romazicon) Indication
Reversal of respritory depression and the sedative effects from pure Benzodiazepine OD
Flumazenil(Romazicon) Contraindications
Hypersensitivity
Tricyclic antidepressant OD
Seizure prone Pts
Coma of unknown etiology
Flumazenil(Romazicon) Adverse
Nausea/Vomiting
Agitation
Visual Disturbances
Seizures
Flumazenil(Romazicon) Dosage
Adult:
1st 0.2mg IV/IO over 15sec
2nd 0.3mg IV/IO over 30sec
3rd 0.5 IV/IO over 30sec
If no response repeat once every minute until adequate response or a total of 3mg
Peds: Not recommended