Flumazenil(Romazicon) Class Benzodiazepin receptor antagonist Note to self Flumazaenil is to Benzo as Narcan is to Opiod Flumazenil(Romazicon) MOA Antagonizes the actions of benzodiazepines on the CNS Flumazenil(Romazicon) Indication Reversal of respritory depression and the sedative effects from pure Benzodiazepine OD Flumazenil(Romazicon) Contraindications Hypersensitivity Tricyclic antidepressant OD Seizure prone Pts Coma of unknown etiology Flumazenil(Romazicon) Adverse Nausea/Vomiting Agitation Visual Disturbances Seizures Flumazenil(Romazicon) Dosage Adult: 1st 0.2mg IV/IO over 15sec 2nd 0.3mg IV/IO over 30sec 3rd 0.5 IV/IO over 30sec If no response repeat once every minute until adequate response or a total of 3mg Peds: Not recommended