Heparin Class Anticoagulant Heparin MOA Direct inhibitor of thrombin Heparin Indication ACS Pulmonary edema Heparin Contraindications Should not be used unless medically necessary Active bleeding Recent trauma Known hypersensitivity to drug/beef/pork Heparin Adverse Confusion Edema Fever Bruising Bleeding complications Heparin Dosage Adult: Loading - 60units/kg IV(max 4,000units) Maintenance - 12units/kg/hr(max 1,000units/hr) Peds: 50units/kg followed by infusion