What would result in the presence of spherocytes on the peripheral blood smear? What about schistocytes? Spherocytes are present in patients with hereditary spherocytosis or immune-mediated hemolysis. The presence of schistocytes suggests a microangiopathic hemolytic anemia or mechanical shearing of erythrocytes (Mayo Clin Proc, Vol. 84, pg. 281). Name the 4 metabolic derangements associated with the Tumor Lysis Syndrome. Hyperuricemia Hyperphosphatemia Hyperkalemia Hypocalcemia (Mayo Clin Proc, Vol. 81, pg. 838).