Lidocaine Hydrochloride (Xylocaine) Class Anti-arrhythmic Lidocaine Hydrochloride (Xylocaine) MOA Decrease automaticity by slowing rate of phase 4 depolarization Supresses ventricular ectopy Increases the fibrilation threshold Lidocaine Hydrochloride (Xylocaine) Indication Malignant PVCs V-Tach V-Fib Sometimes as premed for RSI Lidocaine Hydrochloride (Xylocaine) Contraindication Hypersensitivity 2nd/3rd degree hb Wide complex ventricular escape beats with bradycardia Lidocaine Hydrochloride (Xylocaine) Adverse Reaction Slurres speech Seizure AMS Confusion Lightheaded Blurred vision Bradycardia Lidocaine Hydrochloride (Xylocaine) Dosage Adult: Inital 1-1.5 mg/kg IV/IO may repeat in 5-10min at 0.5-0.75 mg/kg to a max dose of 3 mg/kg ET: 2-4 mg/kg Stable V-Tach: 0.5-0.75 mg/kg and up to 1-1.5 mg/kg repeat 0.5-0.75 mg/kg to a max dose of 3 mg/kg Maintence Infusion: 1-4 mg/min in NS or D5W