Pathology 4

Card Set Information

Author:
zf2010
ID:
100264
Filename:
Pathology 4
Updated:
2011-09-07 03:36:41
Tags:
USUHS Pathology Hemodynamic disorders Thromboembolic Disease Shock
Folders:

Description:
Pathology 4
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user zf2010 on FreezingBlue Flashcards. What would you like to do?


  1. Edema
    • Any abnormal increase in interstitial fluid
    • ex. hydrothorax, hydropericardium
  2. Ascites
    • Edema in the peritoneum
    • aka hydroperitoneum
  3. Anasarca
    Severe and generalized edema with widespread subcutaneous tissue swelling
  4. Transudate vs Exudate
    • Transudate is protein-poor
    • Exudate is protein-rich
  5. What cardiac pathology commonly causes pulmonary edema?
    Left ventricular failure
  6. Hyperemia
    • Active process of arteriolar dilation
    • Results in increased blood flow
  7. Congestion
    State resulting from reduced outflow of blood from a tissue
  8. Thrombosis
    Formation of a thrombus within an intact vessel
  9. Prostacyclin (PGI2)
    • Endothelium-derived prostaglandin
    • Inhibits platelet aggregation
    • Potent vasodilator
  10. Thromboxane (TxA2)
    • Platelet-derived prostaglandin
    • Activates platelet aggregation
    • Vasoconstrictor
  11. Thrombin
    • Product of the coagulation cascade
    • Converts fibrinogen to fibrin
  12. Virchow's Triad
    • Abnormalities that lead to thrombus formation:
    • 1. Endothelial injury
    • 2. Statis or turbulent bloow flow
    • 3. Hypercoagulability of the blood
  13. Leiden Mutation
    • Mutation in the antithrombotic factor V
    • Increased risk for thrombosis
  14. Heparin-induced thrombocytopenia syndrome
    • Antibodies created in response to unfractionated heparin administration
    • Antibodies react with heparin-like molecules
    • Activation and aggregation of platelets results
  15. Embolization
    • Dislodgement of the thrombus
    • Travels to other sites in vasculature
  16. Dissolution
    • Destruction of a thrombus
    • Via fibrinolysis
  17. Phlebothrombosis
    • Venous thrombosis
    • Most significant is DVT - often embolize
  18. Disseminated Intravascular Coagulation
    Widespread activation of the coagulation cascade and fibrin thrombi formation in microcirculation
  19. Embolism types
    • Pulmonary embolism
    • Systemic thromboembolism
    • Fat and marrow embolism
    • Air embolism
    • Amniotic fluid embolism
  20. Types of shock
    • Cardiogenic shock
    • Hypovolemic shock
    • Septic shock
    • Other: Neurogenic shock, Anaphylactic shock
  21. Stages of shock and descriptors
    • Nonprogressive Stage - compensatory mechanisms maintain perfusion
    • Progressive Stage - Tissue hypoperfution
    • Irreversible Stage - Massive cellular and tissue injury

What would you like to do?

Home > Flashcards > Print Preview