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Cephalosporin's are structurally and chemically related to __________.
Cephalosporins are considered to be ___-_____ antibiotics.
____-________ may occur between penicillins and cephalosporins, meaning that allergy to one class may indicate __________ to the other in some clients.
When dealing with the 4 generations of cephalosporins, the first through third generations increased activity against ____-_____ organisms and ________; less active against ____-______ organisms; first generation does not enter the ____ and has limited activity against _____ ___-_______ organisms.
- aerobic gram-negative
When dealing with the 4 generations of cephalosporins, the fourth generation increases activity against gram-_____ ___ and gram- _____ ____
- gram-positive cocci
- gram-negative bacilli
The 3rd generation is effective against ___ caused by ______ _______.
- neiserria gonorrhoeae
________ is commonly associated with gonorrhea so client may be given ________ (________) as a single dose or ________ (________) concurrently.
- a-zithro-my-cin (zithromax)
- doxy-cycline (vibramycin)
Most cephalosporins are excreted through urine except _________ ( ) and ________ ( ), which are excreted in ____.
- ce-fo-pera-zone (cefobid)
- cef-triax-one (rocephin)
List the common 1st generation cephalosporins: (5)
- ce-fa-droxil (Duricef)
- ce-fa-zolin (Ancef)
- ce-pha-lexin (Keflex)
- ce-pha-pirin (Cefadyl)
- ce-phra-dine (Velosef)
List the common 2nd generation cephalosporins:
- ce-fa-clor (Ceclor)
- ce-f-meta-zole (Zefazone)
- ce-f-pro-zil (Cefzil)
- ce-fo-tetan (Cefotan)
- ce-fox-itin (Mefoxin)
- ce-fur-oxime axetil (Ceftin)
- ce-fur-oxime sodium (Zinacef)
- loracarbef (Lorabid)
List the common 3rd generation cephalosporins:
- ce-f-dinir (Omnicef)
- ce-fix-ime (Suprax)
- ce-fo-pera-zone sodium (Cefobid)
- ce-fo-tax-ime (Claforan)
- ce-f-podo-xime proxetil (Vantin)
- ce-f-taz-idime (Fortaz)
- ce-f-di-toren (Spectracef)
- ce-f-ti-buten (Cedax)
- ce-f-tiz-oxime (Cefizox)
- ce-f-tri-axone (Rocephin)
List the common 4th generation cephalosporins:
When dealing with cephalosporins a contraindication is cross-sensitivity with?
Cephalosporins interfere with bacterial cell ____ _______ and are considered _____-_______.
- cell wall synthesis
- broad spectrum