test 1

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  1. Hyperpigmentation: darkening of the skin, particularly in creases and skin folds
    Addison's disease caused by increased secretion of melanocyte-stimulating hormone, acanthosis nigricans
  2. Striae: puplish red marks below the skin surface-usually seen on abdomen, breasts and buttocks
    Cushing syndrome
  3. Changes in skin texture:
    1.thick cold, dry skin
    2.thick, leathery, oily skin
    3. warm, smooth mosit skin
    • 1.Hypothroidism
    • 2. growth hormone excess (agromegaly)
    • 3. hyperthyroidism
  4. Changes in hair distribution
    1. hair loss
    2. diminished axillary and pubic hair
    3. hirsutims(excessive facial hair on women)
    • 1. hypothyroidism, hyperthyroidism, decreased pituitary secretion
    • 2. cortisol deficiency
    • 3. Cushing syndrome, prolactinoma(pituitary tumor)
  5. Skin ulcerations:
    areas of ulcerated skin, most commonly found on the legs and feet
    Peripheral neuropathy and peripheral vascular disease are contributing factors in the development of diabetic foot ulcers
  6. Edema: generalized edema
    Mucopolysaccharide accumulation in tissue in hypothyroidism
  7. Visual changes:decreased visual acuity and/or decreased peripheral vision
    Pituitary gland enlargement/tumor leads to pressure on optic nerve
  8. Expophthalmos:eyeball protrusion from orbits
    Occurs in hyperthyroidism as a result of fluid accumulation in eye and retroorbital tissue
  9. Moon face:periorbital dedema and facial fullness
    Cushing syndrome as a result of increased cortisol secretion
  10. Myxedema:puffiness, periorbital edema, masklike effect
    Hydrophilic mucopolysaccharides infiltrate dermis in patients with hypothyroidism
  11. Goiter:generalized enlargement of thyroid gland
    Hyperthyroidism, hypothyroidism, iodine decifiency
  12. Thyroid nodules:localized enlargement of thyroid gland
    may be benign or malignant
Card Set:
test 1

table 48-7
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