PHARMACOLOGY

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Author:
rgoss1
ID:
100389
Filename:
PHARMACOLOGY
Updated:
2011-09-07 20:41:49
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RX CLASS
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Description:
Pharm Exam I
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  1. ACTION: Inhibits transmission
    of reflexes at spinal cord level (spasmolytics)

    INDICATION: TX of cerebral spasticity, reversible spasticity associated with MS or spinal cord lesions
    • Central-Acting Skeletal muscle relaxant
    • baclofen/Lioresal
    • Preg-C
  2. ACTION: Acts directly on skeletal muscle, causing relaxation by decreasing calcium release from sarcoplasmic reticulum in muscle cells

    INDICATION: Muscle spasms Prophylactic for malignant hyperthermia Emergency TX of malignant hyperthermia
    Preg: C
    • Direct-Acting Muscle Relaxant
    • Dantrolene/ Dantrium
  3. ACTION: CNS DEPRESSANTS THAT INHIBIT NEURONAL IMPULSE CONDUCTION, DEPRESS CEREBRAl CORTEX, ALTER CEREBELLAR FUNCTION, AND DEPRESS MOTOR OUPUT
    INDICATION: Relief of S & S of anxiety, sedation,
    insomnia, preanesthesia, and TX of seizures
    Preg: D
    Sched: IV
    • Barbituate
    • Phenobarbital/Luminal
  4. ACTION: CNS depressant Promotes skeletal muscle relaxation by inhibiting afferent pathways. Anti-convulsant properties
    INDICATION: Anxiety, sedation, amnesia, skeletal muscle relaxation, decrease seizures, ETOH withdrawal
    Preg: D
    Sched IV
    • Benzodiazepine
    • diazepam/Valium
    • antidote=flumazenil
  5. ACTION: Selective tothe mu receptor. Main effect is in the brain
    INDICATION: For moderate to severe chronic and acute pain. Pre-op, post-op and during labor
    Preg: C
    • Opioid agonist
    • morphine/Roxanol
  6. ACTION: Complete/partial block of opioid effects (CNS/resp depression without producing agonist (opioid like) effects
    INDICATION: Reversal of signs of opioid excess
    Preg: B
    • Opioid antagonist
    • naloxone/Narcan
  7. ACTION: Binds to opiate receptors in CNS. Agonist affects response to painful stimuli. Antagonist may result in opioid withdrawal in physically dependent PTs.
    INDICATION: Relief of moderate to severe pain in L & D, postpartum pain; adjunct to general anesthesia.
    Preg: C
    • Opioid Agonist/Antagonist
    • pentazocine/Talwin
  8. ACTION: Vasoconstricts blood vessels by stimulating alpha-adrenergic receptors 5-HT. This vasoconstricts vessels in the brain
    INDICATION: TX of vascular headaches including migraines with or without aura and cluster headaches
    Preg: X
    • Ergot Alkaloids
    • ergotamine
  9. ACTION: Selective agonist of 5 HT-1 at specific vascular serotonin receptor sites, causing vasoconstriction in large intracranial arteries.
    INDICATION: Acute TX of migraine attacks
    Preg: C
    • Triptans
    • sumatriptan/Imitrex
  10. ACTION: Inhibit synthesis of prostaglandin; blocks pyrogens; inhibits PLT aggregation. 4A's antipyretic, antiinflammatory, antiplatelet, analgesic
    INDICATION: Mild to moderate pain, fever, inflammatory conditions. Reduce risk of TIA and MI
    Preg: Not indicated d/t risks to mother
    • Salicylates
    • acetyl Salicylate Acid (ASA)
  11. ACTION: Inhibits prostaglandin syntheses. Decreases pain, inflammation, and reduces fever.
    INDICATION: Relief of pain, fever, inflammation
    Preg: C up to 30 weeks, then D
    • Non-opioid analgesic
    • ibuprofen/Advil
  12. ACTION: Works directly on thermoregulatory cells to cause sweating and vasodilation.
    INDICATION: Mild to moderate pain, fever, M/S pain r/t arthritis
    • Non-salicylate
    • acetaminophen/Tylenol
  13. ACTION: gold containing chemical (salt) Reduce Inflammation of joint lining
    INDICATION: Rheumatoid Arthritis
    Preg: C
    • Anti-Arthritis
    • AUROTHIO GLUCOSE

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