Cardio

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Author:
mct12188
ID:
100799
Filename:
Cardio
Updated:
2011-09-10 00:27:05
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cardio
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Description:
Intro to cardio 1
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  1. p wave
    –Atrial systole

    • –Signal from SA node spreads through
    • atria and depolarization begins

    • –Correlates with phase 0 of
    • myocardial action potential
  2. QRS complex
    • –Firing of AV node and ventricular
    • depolarization

    • –Atrial repolarization and
    • diastole

    • –Correlates with phase 1 of
    • myocardial action potential
  3. S-T segment
    –Ventricular systole

    –Contraction and ejection of blood

    • –Correlates with phase 2 of
    • myocardial action potential
  4. T wave
    –Ventricular repolarization

    • –Immediately before ventricular
    • diastole

    • –Correlates with phase 3 of
    • myocardial action potential
  5. ECG - the 5 waves
  6. Qt prolongation
    Genetic or acquired

    Caused by drugs and electrolyte abnormalities

    • –Antiarrhythmics, antipsychotics, antibiotics,
    • methadone

    –Hypokalemia, hypomagnesemia
  7. Angioplasty
    • Procedure to open blocked or narrowed coronary arteries
    • Done during the left cardiac catheterization
    • Balloon angioplasty alone or with stent placement
  8. CABG
    Coronary artery bypass grafting

    nOpen heart surgery

    nGrafts harvested from legs, chest, or arms

    nGrafts are used as a “detour” around the blocked portion of the coronary artery
  9. COAGULATION FACTORS

    1. vitamin k dependent
    2. thrombin sensitive
    • 1. - 2, 7, 9, 10
    • 2. - 5, 8, 13, fibrinogen
  10. anticoagulants
    • —Prevent/treat venous thrombi
    • **prevents clots from getting bigger
    • VTE --> PE, DVT

    composed mainly of fibrin and RBCs = red clots
  11. antiplatelets
    • prevent/treat arterial thrombi
    • - MI, stroke, limb gangrene

    composed mainly of platelets = white clots
  12. anticoagulant drugs
    • vitamin k antagonists (warfarin)
    • heparin
    • factor Xa inhibitors
    • direct thrombin inhibitors
  13. antiplatelet drug therapy
    • asparin
    • ADP inhibitors
    • - thienopyridines (clopidogrel)
    • - cyclopentyltriazolopyrimidine (ticagrelor)
    • Phosphodiesterase inhibitors
    • glycoprotein 2b/3a inhibitors
  14. Fibrinolytics - thrombolytics
    Dissolving existing clots

    use: plasminogen activators
  15. Drug group summary

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