muscoskeletal extra

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  1. MOA: Inhibits bone resorption SE: Patients may experience localized skin reaction to the injection or systemic reaction if allergic to salmon
    Calcitonin - Miacalcin Nasal Spray, Fortical Nasal Spray
  2. MOA: Provides calcium for bone formation U: treats post menopausal osteoporosis and prevention of progressive bone loss
    Calcium Carbonate - Oscal
  3. SE: Hot flashes Peripheral edema leg cramps/muscle spasm
    Raloxifene - Evista
  4. DI: Take with food or milk Avoid aspirin May cause drowsiness Do not drink alcohol SE: G.I. Upset
    All NSAIDS
  5. Use: Anti-inflammatory, Analgesic, 1st line for gouty arthritis
    Indomethacin - Indocin
  6. Use: Anti-Inflammatory & Analgesic ~also marketed as immediate release Potassium Salt (Cataflam)
    Diclofenac - Voltaren
  7. Uses: Osteoarthritis, Rheumatoid arthritis and Juvenile Rheumatoid arthritis
    Meloxicam - Mobic
  8. Considered a Schedule III-V drug Commanders will consider it a locally controlled item
  9. Considered a Schedule III-V drug
    Isometheptene Mucate, Dichloralphenazone, Acetaminophen - Midrin
  10. Intoxication or poisoning due to an overdose or excessive use of the ergot alkaloids is known as ...........
  11. Use: Abort or prevent vascular headaches (migraines) Controls effectively up to 70% of acute migraine attacks *contraindicated in pregnancy* SE: Vertigo, itching, nausea and vomiting
    Ergotamine Tartrate - Ergomar
  12. Migranal is a ____________ DHE45 is a ______________
    nasal preparation injectable
  13. A new class of anti-migraine agents that work primarily on the serotonin receptor causing cerebral vasoconstriction
  14. MOA: Reduces the production of uric acid
    Allopurinol - Zyloprim, Aloprim
  15. MOA: Increases urinary excretion of uric acid
    Probenecid - Benemid
  16. What does DMARD stand for?
    Disease Modifying Anti-Rheumatic Drug
  17. Agents that completely block nerve impulses to skeletal muscles causing complete skeletal muscle relaxation
    Neuromuscular Blocking Agents
  18. Agents cause complete blocking of nerve impulses so most pharmacists do not strictly consider them skeletal muscle relaxants
    Neuromuscular Blocking Agents
  19. When nerve impulses that stimulate skeletal muslce tone become blocked at the spinal cord and results in diminished skeletal muscle tone
    Skeletal Muscle Relaxation
  20. Three major categories of skeletal muscle relaxants
    Neuromuscular Block Agents Centrally Acting Agents Direct Acting Agents
  21. The onset of blockade is usually rapid as motor weakness gives way to
    total flaccid paralysis
  22. What 2 drugs are short acting NMBs with an onset of ~1 minute and a duration of action less than 30 minutes?
    Mivacurium - Mivacron Rapacuronium - Raplon
  23. An acetylcholinesterase inhibitor used to antagonize or reverse the action of these agents
    Neostigmine - Prostigmin
  24. MOA: acts like an excess of acetylcholine at NM junction to depolarize the muscle receptor site and prevent its repolarization-causes an initial muscle contraction
    Depolarizing blocking agents
  25. Use: ultra-short acting neuromuscular blocking agent used as an adjunct to anesthesia or for rapid sequence intubation (short procedures Is the only depolarizing agent approved for use in the U.S.
    Succinylcholine - Anectine, Quelicin
  26. Use: Muscle spasticity and rigidity associated with multiple sclerosis or cerebral palsy, also spinal cord injuries SE: Frequent urination
    Baclofen - Lioresal
  27. MOA: Reduces skeletal muscle tone through a direct effect on contraction.
    Direct Acting Skeletal Muscle Relaxants
Card Set:
muscoskeletal extra
2011-09-12 18:02:01
Therapeutics II

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