ATROPINE

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Author:
Kylecon40
ID:
102171
Filename:
ATROPINE
Updated:
2011-09-16 16:24:33
Tags:
ATROPINE
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Description:
DRUGS
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  1. Class:
    Parasympatholytic
  2. Trade name:
    Atropine
  3. Description:
    Atropine is derived from the Atropa belladonna plant. Selectively blocks responses to acetylcholine (ACh), and blocks vagal impulses to the heart.
  4. Actions:
    • 1. Competes with acetylcholine for receptor sites blocking the PNS response at SA & AV nodes.
    • 2. Increases rate of SA node discharge
    • 3. Enhances conduction through the AV node
    • 4. Increases heart rate by increasing electrical conduction through the heart.
    • 5. Increases cardiac output
    • 6. Systemically counteracts effects of parasympathetic stimulation. Inhibits secretions by decreasing PNS effect on bronchial, salivary, sweat and GI glands.
  5. Indications:
    • 1. Hemodynamically significant bradycardia
    • 2. Asystole
    • 3. Organophosphate poisoning
  6. Contraindications:
    No contraindications in the emergency setting
  7. Side Effects:
    • 1. Tachycardia
    • 2. Blurred vision, dilated pupils
    • 3. Dry mouth
    • 4. Confusion, drowsiness
  8. Administration
    • Asystole, or PEA
    • Adult max 0.03 mg/k
    • 1 mg IV/IO, 2 mg ET q 3-5 min
    • Peds max 0.03mg/k
    • Hemodynamically unstable bradycardia
    • Adult: 0.5-1 mg, 2 mg ET q 3-5 min
    • Ped: 0.02 mg/kg IV

    • Organophosphate poisonings(No Max)
    • Adult: 2-5 mg IV/IM
    • q 10- 15min
    • Peds: IV 0.05 mg/kg IV/IM

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