CNS Blood Supply (Welke)

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Author:
catitasilva
ID:
102451
Filename:
CNS Blood Supply (Welke)
Updated:
2011-12-09 09:22:41
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blood supply
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CNS blood supply
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    • 1. Posterior Spinal Artery
    • occlusions: loss of T/P/P
    • 2. Anterior Spinal Artery
    • occlusions: B/L loss of P/T & paralysis NO changes T/P/P
  1. What are the 2 systems that supply the brain?
    • Internal Carotid Arterial System
    • Vertebral/Basilar Arterial System
    • 1. Anterior Communicating Artery
    • 2. Anterior Cerebral Artery
    • 3. Internal Carotid Artery
    • 4. Posterior Communicating Artery
    • 5. Posterior Cerebral Artery
    • 1. Posterior Cerebral A.
    • 2. Paramedian branches(basilar)
    • 3. Circumferential branches(basilar)
    • 4. Superior Cerebellar A.
    • 5. Anterior Inferior Cerebellar A.
    • 6. Posterior Inferior Cerebellar A.
    • 7. Lateral branches (vertebral)
    • 8. Paramedian branches & Ant. Spinal A. (vertebral)
  2. Systems supplying the Brain?
    • Internal Carotid
    • Vertebral/Basilar
  3. Internal Carotid Branches?
    • Ophthalmic A.: eyeball & orbital structures
    • Ant. Choroidal A.: choroid plexus, thalamus & hippocampus
    • Post. Communicating A.: connects to Post. Cerebral A.
    • Middle Cerebral A.: lateral cerebral hemisphere & insula
    • Ant. Cerebral A.: medial aspect of frontal & parietal lobes
  4. Middle Cerebral Artery
    Where is it?
    What does it supply?
    Occlusions?
    • Lateral Sulcus
    • Lateral Cerebral Hemisphere (most of motor & somatosensory gyri) & Insula
    • restricted C/L motor & somatosensory deficit
  5. Anterior Cerebral Artery
    Where is it?
    What does it supply?
    Occlusions?
    • Longitudinal Fissure
    • Medial aspect of frontal & parietal lobes
    • C/L motor & somatosensory deficit of the lower limb
  6. Vertebral Artery Branches?
    • Ant. Spinal: anterior medial fissure
    • Post. Spinal: postero-lateral sulcus
    • Post. Inf. Cerebellar A.: inferior cerebellar, lateral medulla choroid plexus & 4th ventricle
  7. Inferior Alternating Syndrome
    • lesion in the ant. spinal a. in the medulla
    • Affects:
    • Corticospinal tract (C/L voluntary motor)
    • Medial Lemniscus (C/L touch)
    • Hypoglossal N. (I/L voluntary motor of tongue)
  8. Lateral Medullary Syndrome?
    • Wallenberg's Syndrome
    • lesion of PICA
    • Affects:
    • Inf. Cerebellar peduncle (ataxia)
    • Spinothalamic Tract (C/L pain)
    • Sympathetic Fibers (Horner's)
    • NA (hoarseness)
    • NS (loss of taste & cardiorespiratory)
  9. Basilar Artery Branches?
    • AICA: ant, inf, cerebellum & parts of pons
    • --> labrynthe a.: inner ear (x vertigo/deafness)
    • Sup. Cerebellar A.: sup cerebellum (x ataxia)
    • Posterior Cerebral A.: medial, inf occipital & temporal lobes
    • Long Circumferrential Branches
    • Paremdian Pontine A.
  10. Superior Alternating Syndrome
    • Weber's Syndrome
    • occlusion of Posterio Cerebral A. (PCA)
    • U/L damage to ventral midbrain
    • I/L occulomotor n. palsy
    • C/L hemiplegia
  11. Compostion of BBB
    • endothelial cells
    • tight junctions of capillaries
    • supporting cells - astrocytes
  12. Importance of BBB?
    • functions in preventing/slowing the passage of substances
    • a benefit and hindrance (pharm)
  13. Complete breakdown of BBB
    Brain tumors
  14. Subtle barrier impairment w/o end organ damage
    • Disease states:
    • MS
    • Alzheimer's
    • HIV
    • Stroke
    • Diabetes
    • Eating/weight disorders
  15. Disturbances in Vascular Supply:
    Stroke
    thrombus or embolism
  16. Disturbances in Vascular Supply:
    TIA-Transient Ischemic Attack
    minute particles
  17. Disturbances in Vascular Supply:
    Anneurysm
    arterial wall swelling that can rupture
  18. Disturbances in Vascular Supply:
    Watershed
    dual blood supply

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