Test I

trade name

molecules that contain at least one atom of nitrogen and carry a positive charge all times

proton donor

proton acceptor

process of an acid giving up a proton or a base accepting a proton and converting the acid or base into a charged particle

two pathologic conditions in which low blood flow can affect drug therapy

inflammation of the colon caused by antibiotics (suprainfection; bacteria C. difficile)

two types of Oral Contraceptive

Two types of Hormone replacement therapy:

why is progestin given along with estrogen in hormone replacement therapy? and what can it lead to if progestin is not given?

act on the uterus to cause the proliferation of the endometrium

together these two hormones regulate the menstraul cycle

acts on ovarian follicles, causing them to mature and secrete estrogens

influences corpus luteum to secrete progesterone

support the development and maintenance of the female reproductive tract and secondary sex charachteristics, required for the growth and maturation of the uterus, vagina, fallopian tubes, and breasts

prepares the uterus for implanctation of a fertilized ovum and help maintain the uterus throughout pregnancy

injection given to neonates immediately after delivery

suppression of preterm labor; uterine relaxants

induction/augmentation of labor, control of postpardum bleeding and induction of abortion; uterine stimulants

receptor antagonist, peptide hormone produced by the posterior pituitary.

Increases the force, frequency, and duration of uterine contractions. used to help uterus close after delivery and to control postpartum hemorrhage

can suppress labor up to 48 hours

treatment of fungal infections. highly toxic and dangerous with side effects including flushing, fever, chills, hypotension, red man's syndrome

used for suprainfections with susceptible organisms in patients allergic to penicillin.

inhibits cell wall synthese and promotes bacterial lysis.

side effects include ototoxicity, flushing, rash, tachycardia, hypotension

suprainfection of the bowel from bacteria C. diffile

characterized by profuse watery diarrhea, abdominal pain, fever

treated with vancomycin

polyene antibiotic used for candidiasis

polypeptide antibiotic used for topical treatment of bacterial infections.

adverse reactions include: renal dysfunction, blood dyscrasias, respiratory distress

a macrolide with a broad antimicrobial spectrum; preferred treatment for a number of infections. safer antibiotic

binds to the 50S ribosomal subunit and therby blocks addition of new amino acids in the peptide chain

can increase the plasma levels and half lives of several drugs thereby posing a risk for toxicity

side effects include nausea, vomitting, diarrhea, abdominal crams, liver toxicity if taken with other hepatotoxic drugs (ex- acetaminophen)

broad spectrum antibiotics that inhibit bacterial protein synthesis

the ratio of the minimum concentration of drug that produces toxic effects and the minimum concentration that produces the desired effect

often used to refer to the span of concentration between minimum toxic concentration and minimum effective concentration. the bigger the easier to administer a drug without unwanted toxicity

done to find out what kind of organism is causing an illness or infection

test done to check to see what kind of medicine will work best to treat the illness or infection

define the term "generation" as it relates to cephalosporins:

What is unique about 3 and 4 generation cephalasporins?

suppress bacterial growth by inhibiting protein synthesis