Assessment 1.2

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Assessment 1.2
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2011-09-19 19:09:24
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Assesment 1.2
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  1. What two Amino Acids contain sulfur atoms?
    Methionine and cysteine
  2. Proline
  3. Which of the following compounds is a sodium salt of glutamic acid?
    MSG
  4. Which of the following neurotransmitters is a precursor for serotonin?
    Tryptophan
  5. An amino acid that is NON essenestial and associated with heart disease?
    Homocysteine
  6. What is the disadvantage of a oral peptide drug?
    LOW Bio-availability
  7. Which disease is cx by GLY12--> Val cx enzyme "RAS" to become active
    Cancer
  8. Which amino acid would most likely not be present in an ALPHA-helicial structure of protein?
    Proline
  9. Properties of Fibrous Proteins

    3

    SFE
    Stiff

    Elongated Proteins

    Form from insoluble fibers
  10. A prothesthetic group of a protein is a non-protein structure that is
    permanently associated with the protein
  11. What step occurs last during the sliding filaments of muscle?
    Power Stroke

    Pi released from myosin

    cx hinge to close
  12. Monoclonal antibodies are those produced by
    by a population of identical B cells (a clone) responding to one single epitope of a protein.
  13. This drug is a recombinant, human mouse chimeric monoclonal antibody
    binds specifically to the extracellular domain of the human epidermal growth factor receptor(EGFR)

    What drug is it
    Erbitux (cetuximab)
  14. Which of the following processes requires caspases?
    Apoptosis
  15. Phosphatidylcholine is from which class of membrane lipids?
    Glycerophospholipids
  16. Which of the following processes ends with a membrane fusion event?
    Exocytosis
  17. Macroautophagy
    The process by which lysosomes recycle organelles
  18. describes the function of intermediate filaments
    Provides tensile strength in the cell
  19. Is cystol an organelle
    NO
  20. This receptor is named for its endogenous ligand
    Andrenergic receptor
  21. Prodrugs are active or inactive when administred
    Inactive
  22. Glutathione and N-acetyl cysteine can be used to treat an acetaminophen overdose because
    They both contain a thiol
  23. When induction occurs, what happens
    prodrugs and drugs are metabolized more due to drug-drug interactions
  24. Biotransformation does what to the structure of the drug
    makes the drug more polar
  25. Why does biotransformation make the structure of the drug more polar
    to become more reactive within the body.
  26. Lipitor (Atorvastatin) in a competitive or non-competitve inhibitor of HMG CoAce Reductase
    Competitive

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