blood

• All the phils!
• Neutrophils (60-70%), Eosinophils (2-4%), Basophils (1%)
• Phagocytosis and inflammatory response

• Donate to AB-, AB+
• Receive from AB-, A-, B-, O-

• Clotting from coagulation
• Fibrin fibers branch like a dam
• (Requires clotting factors from the liver and calcium from the blood)

Platelets

Polycythemia

When platelets stick together

• Activation of platelets by collagen (blood trauma)
• Platelets factor
• Clotting factor X (10)

• Lymphiod stem cell
• Myeloid stem cell

• Spherical nucleus
• agranular
• fx = immunity
• 20-30%

Leukocytosis

• Red Blood Cell (RBC)
• it has no nucleus
• contains 250 million hemoglobin molecules

Erythrocyte (RBC) formation

• Donate to anyone!!! Universal donor
• Receive from only O-

Transferrin

• supplied by regular diet
• recycled from cells and stored in the liver and spleen
• Amino acids, iron, vitamin B12

• Damage tissue (tissue trauma)
• Tissue factor
• Clotting factor VII (7)

• Make up 60% of the 7% of plasma protiens
• Maintains osmotic pressure of the plasma

• Donate to A+, B+, AB+, O+
• Receive from O+, O-

• Donate to AB+ only!!!
• Reveive from anyone! Universal recipient!!!

The hormone that stimulates platelet formation

• Monoblast
• Myeloblast

• 7% of plasma
• Albumins 60%
• Globulins 35%
• Fibrinogen 4%
• Regulatory proteins 1%

Blood clotting to stop bleeding

• Reticulocyte
• then to a mature RBC

• Water 92%
• Plasma proteins 7%
• Other solutes 1%

White Blood Cell (WBC)

• Segmented nucleus
• Granulated
• Phagocytosis
• 60-70%

The mother cell of every cell in the blood

A blockage of a vessel due to a clot

• Hemolysis occurs in the blood
• Liver and spleen phagocytes eat them

• Lymph tissues for lymphocytes
• Red bone marrow for monocytes, neutrophils, basophils and eosinophils

• Donate to B-, B+, AB-, AB+
• Receive from B-, O-

• Hemocytoblast
• Myeloid stem cell
• Megakaryocyte
• Platelets (Thrombocytes)

Leukopenia

• Kidney shaped
• agranular
• tissue macropahges
• 4-8%

• Stercobilin
• Shit!

Monocyte

• Splits into heme and globin
• Amino acids of the globin is recycled
• Heme splits releasing the iron which is recycled
• Heme to bilirubin to urobilin to urine
• or
• Heme to bilirubin to stercobilin to shit

Lymphocyte

• (anticoagulant)
• Antagonist of Vitamin K

Anemia

Thrombus

80-120 days

Platelets plug formation

Factor VII + Factor X = Prothrombinase

Bilirubin leaks into blood

Abnormal RBC in the shape of a moon

Myeloid stem cell

A moving clot

Hemocytoblast

Ferritin

Low platelet count

The lack of blood coagulation

The liver

• Urobilin
• Urine

• The cytes
• Lymphocyte and Monocyte
• Antigen-antibody reactions
• macrophages

• Makes up 4% of the total 7% of plasma proteins
• It is essential for clotting blood

Disease that cause high WBC's

• 1. Iron (Heme)
• 2. Amino Acids (Globin)
• 3. Vitamin B12 (Maturation)

When blood types are not compatible the oppising antibodies will agglutinate and hemolysis will occur and fatal circulatory shock occurs leading to death

• 4 irons that bind to 4 Heme
• Each iron molecule binds with 1 O₂ molecule
• Makes 2 alpha and 2 beta chains
• Globin is the protein

• 1. Neutrophils 60-70%
• 2. Lymphocytes 20-30%
• 3. Monocytes 4-8%
• 4. Eosinophils 2-4%
• 5. Basophile 1%
• Never Let Monkeys Eat Bananas

• Bilobed nucleus
• Granulated
• Big purple lump
• Fx = inflammation
• 1%

• Hemoglobin transports 97% of O₂
• Hemoglobin transports 23% of CO₂
• Hemoglobin releases nitric oxide (regulation of blood flow)

• When mom is Rh- and dad and baby are Rh+
• the mother must go thru desensitization before the next pregnancy or the 2nd baby will die

The percent of each type of WBC

• Donate to B+, AB+
• Receive from B+, B-, O+, O-

• 35% of the 7% of plamsma proteins
• Its functions is immunity

• Vascular spasm
• Decreased loss of blood
• Contraction of smooth muscle of the injured vessel

• Immune response
• Phagocytosis

• 1. Erythrocyte (RBC)
• 2. Thrombocytes (platelets)
• 3. Basophils
• 4. Eosinophils
• 5. Neutrophils
• 6. Monocytes

Anticoagulants

• ALL PHILS!
• Neutrophils
• Eosinophils
• Basophils

Clot dissolving

• 1. Vascular phase
• 2. Platelets phase
• 3. Coagulation phase

• Bilobed nucleus
• Granulated
• Antiinflammatory
• 2-4%

• Makes 1% of the 7% of plasma proteins
• Function is enxymes and hormones

Platelet plug formation in clotting blood

• Donate to A-, A+, AB-, AB+
• Receive from A-, O-

The prenence or absence of the A and B antigens on the RBC surface

• Donate to A+, AB+
• Receive from A+, A-, O+, O-

• 1. Formation of prothrombinase
• 2. Formation of thrombin
• 3. Formation of fibrin fibers

The formation of formed elements in the blood

• (anticoagulant)
• Decreases thrombin production

• Tissue Plasminogen Activator (TPA)
• Activates plasmin which eats the blood clot

• 1. Decreased RBC's
• 2. Tissue hypoxia
• 3. Kidneys excrete erythropoietin hormone
• 4. Bone marrow stimulation
• 5. Production of proerythrocytes
• 6. Erythrocytes
• and repeat untill it is ok again

• (anticoagulants)
• tying up and removing calcium