Histamines Antihistamines

Card Set Information

Author:
skycloud
ID:
103839
Filename:
Histamines Antihistamines
Updated:
2011-09-23 13:00:01
Tags:
histamine antihistamine
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Description:
Histamine Actions and Antagonists
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  1. H1
    • Smooth muscle of blood vessels, bronchi, intestines
    • Endothelium
    • CNS
  2. H2
    • Stomach acid secretion
    • Smooth muscle of some vessels
    • Cardiac muscle
    • Mast cells
    • CNS
  3. H3
    Autoreceptor on histamine releasing neurons
  4. H1 antagonists (1st Generation)
    • Diphenhydramine
    • Promethazine
    • Chlorpheniramine
    • Pyrilamine
    • Cyclizine
    • Meclizine
    • Cyproheptadine
  5. H1 antagonists (2nd Generation)
    • Fexofenadine
    • Loratadine
    • Desloratadine
    • Cetirizine
  6. Other antihistamine compounds
    • Cromolyn sodium
    • Stabilizes mast cells, preventing release of histamine
  7. H2 antagonists
    • Cimetidine (inhibits p450)
    • Ranitidine
    • Famotidine
    • Nizatidine

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