1.) A disadvantage of phenytoin, the maximum infusion rate is _____ mg/min in adults and _____ mg/min in the elderly.
2.) Target serum conc. of phenytoin is _____-_____ mcg/mL
3.) What lab parameter must be considered when dosing phenytoin?
4.) Phenytoin contains propylene glycol, which may cause ______ and ______, and should therefore be avoided in _______ and those with pre-existing ______.
5.) Phenytoin infusions may cause what reactions at injection site?
- 1.) 50 mg/min, 25 mg/min
- 2.) 10-20 mcg/mL
- 3.) Albumin (normal 3.5-5.5 g/dL)
- 4.) hypotension and arrhythmias, elderly patients, cardiac disease (monitor ECG and slow infusion if QT interval widens or these sxs occur!)
- 5.) Phlebitis/tissue necrosis