Parasitology Ch 3

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zf2010
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104019
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Parasitology Ch 3
Updated:
2011-09-24 17:30:03
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Ch 3
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  1. Entamoeba histolytica - Where?
    • Found everywhere
    • Common in tropics
  2. Entamoeba histolytica - How do you get it?
    Infection by ingestion of infective cyst
  3. Entamoeba histolytica - life cycle?
    • Ingested cyst
    • Trophozoite in large intestine (may spread)
    • Feed on RBCs
    • Passed as infective cysts in feces
  4. Entamoeba histolytica - Presentation?
    • Intestinal amebiasis (nonspecific)
    • Diarrhea, abdominal pain
    • Frequent hepatic infection (hepatomegaly, fever)
    • Pulmonary amebiasis
  5. Entamoeba histolytica - Diagnosis?
    • Stool antigen detection
    • serology
    • Biopsy of ulcers
  6. Entamoeba histolytica - Treatment?
    • Metronidazole for invasive infection
    • Paromomycin for intestinal infection
  7. PAM
    Primary amebic meningoencephalitis
  8. Naegleria Fowleri - Where?
    Warm fresh or brackish water
  9. Naegleria Fowleri - How diagnose?
    ID of naegleria in CSF
  10. Naegleria Fowleri -What does it cause?
    • PAM (primary amebic meningoencephalitis)
    • Headache
    • Fever
    • Nausea/vomiting
    • Coma, death within 6 days
  11. Naegleria Fowleri - Treatment?
    • No satisfactory treatment
    • Amphotericin B
  12. Acanthamoeba - How do you get it?
    • Infection of lungs or skin
    • (Keratitis via cornea)
  13. Acanthamoeba - What does it cause?
    • Granulomatous amebic encephalitis
    • Often infection of the cornea
  14. Acanthamoeba - Diagnosis?
    • Biopsy of brain
    • Serology
  15. Acanthamoeba - Treatment?
    Amphotericin B
  16. Balamuthia madrillaris
    Another cause of granulomatous amebic encephalitis
  17. Acanthamoeba keratitis
    Infection of the cornea from acanthamoeba
  18. Giardia lamblia - Where?
    • Worldwide
    • Most common parasite in US
  19. Giardia Lamblia - How do you get it?
    Ingestion of infective cyst
  20. Giardia Lamblia - What does it cause?
    • Diarrhea
    • Flatulence
    • Abdominal pain
    • Fatty stools
    • Malabsorption
  21. Giardia Lamblia - Diagnosis?
    • Stool O&P - may need to collect at intervals days apart
    • Fecal antigen
  22. Giardia Lamblia - Treatment?
    • Metronidazole or tinidazole
    • Albendazole or Mebendazole
  23. Toxoplasmosis
    • Feline parasite - may be seen in immunocompromised individuals
    • Ring-enhancing lesions on brain
    • Afebrile, weakness, poor balance, agitated
  24. Pneumocystic carinii
    • Fungus
    • Interstitial plasma cell pneumonia in immmunocompromised
  25. Cytosporidium Parvum
    • Sporozoa
    • Worldwide
    • Severe diarrhea in immunocompromised
    • Treat with nitazoxanide
  26. Isospora belli
    • Sporozoa
    • Diarrhea in travelers or immunocompromised
  27. Cyclospora cayetanensis
    • Sporozoa causing acute diarrhea
    • Treat with bactrim
  28. Trichomonas Vaginalis
    • Protozoal STI
    • Causes vaginal pruritis, purulent discharge
    • Treat with metronidazole

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