Parisitology - Leishmaniasis

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Author:
zf2010
ID:
104053
Filename:
Parisitology - Leishmaniasis
Updated:
2011-09-24 20:26:49
Tags:
Leishmaniasis
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Description:
Leishmaniasis
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  1. Leishmania vector
    Sandflies
  2. Cutaneous Leishmaniasis - How do you get it?
    • Bite of infected sandfly
    • Contact infection possible
  3. Cutaneous Leishmaniasis - Presentation?
    • Small red itchy papule - grows to ulcer
    • Usually heal spontaneously
    • Lymphadenopathy
  4. Cutaneous Leishmaniasis - Diagnosis?
    • Microscopic ID by aspiration of fluid under ulcer bed
    • Montenegro skin test
  5. Cutaneous Leishmaniasis - Pathogenesis?
    Parasites proliferate as amastigotes in macrophages and endothelium
  6. Cutaneous Leishmaniasis - Treatment
    Sodium stibogluconate (Pentostam)
  7. Mucocutaneous Leishmaniasis - Where?
    S. America
  8. Mucocutaneous Leishmaniasis - Presentation?
    • Ulcers on oral or nasal mucosa
    • Cutaneous lesions, but more frequent and large
    • Nasal septum destroyed (all soft parts of nose and mouth at risk)
    • Death from secondary infection
  9. Mucocutaneous Leishmaniasis - Treatment?
    Sodium stibogluconate (Pentostam)
  10. Visceral Leishmaniasis common name
    Kala-azar
  11. Visceral Leishmaniasis - Differences?
    Protozoa attacks systemically
  12. Visceral Leishmaniasis - Presentation?
    • Hepatospenomegaly
    • Anemia
    • Progressive weight loss
    • Ascites
  13. Visceral Leishmaniasis - Treatment?
    • Sodium stibogluconate (Pentostam)
    • Amphotericin B
  14. Leishmania culture

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