Top 100 - doses

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kvan4741
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105166
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Top 100 - doses
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2011-10-04 09:23:29
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Top 100 AMH PBS drugs pharmacy
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Doses of top 100/commonly dispensed drugs
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  1. Amoxycillin
    250-500mg TDS or 1g BD

    • (MIMS)
    • Adult, children >20kg: 250-500 mg q8h
    • children <20kg: 20-40mg/kg/day in 3 divided doses

    • (AMH)
    • Adult: orally: 250-500mg tds OR 1g BD
    • 1g TDS (severe infections)
    • IM/IV: 1g q6h (max 12g d (severe infections))

    • Child: orally: 7.5-25 mg/kg q8h (80-90mg/kg in severe infections)
    • IM/IV: 10-25mg/kg q8h (max 50mg/kg q4h)
  2. Amoxycillin with Clavulanic acid
    1 BD for 5-10 days

    • AMH:
    • Adult: 500-875mg q12h for 5-10 days or longer depending on infection

    • Children: 7.5-15mg/kg q8h for 5-10 days, max 22.5mg/kg q8h in severe infections
    • Duo product: 12.5-22.5mg/kg q12h

    • acute bacterial sinusitis: tds for 7-14 days
    • UTI: bd for 5 days
    • max 14 days without r/v
  3. Cephalexin
    • 250-500mg QID or 500mg-1g QID-BD
    • UTI Px: 250mg n
    • UTI Tx: 500mg BD
  4. Roxithromycin
    • 1 BD (150)
    • 1 D (300)
  5. Doxycycline
    • 2 stat then 1 d (100) (max 200mg d)
    • Acne: 50mg d
    • Malaria: 1d (100) for 2d before, during and 2-4 weeks after

    • mane preferred
    • DEET
  6. Cefaclor
    1 BD (375mg CD)

    • AMH:
    • Adult: CD: 375-750mg BD (max 4g d) OR 250-500mg q8h
    • Child: 10-15mg/kg q8h OR 20mg/kg q12h (max 1g/dose)

    With food
  7. Di/Flucloxacillin
    250-500mg q6h (max 4g d)

    • AMH:
    • po: 250-500mg q6h (max 4g d)
    • IV: 1-2g q6h, max 12g d

    empty stomach
  8. Metronidazole
    200-400mg TDS (max 4g d)

    • child: 7.5mg/kg q8h
    • tabs with food, liquid 1hr before food
    • EtOH (during + 24 hrs after)
  9. Atorvastatin
    1 d (10/20/40/80)
  10. Simvastatin
    1 n (10/20/40/80)
  11. Irbesartan
    • 1 D
    • usually 150mg d; 300mg if req
    • start at 75mg
  12. Candesartan
    1 d (4/8/16/32 - usu 8; 16 if req)
  13. telmisartan
    1d (usu 20-40; 80 if req)
  14. Nicorandil
    • 10-20mg BD
    • initially 5mg BD

    painful ulcers (any region of GI tract - mouth, perianal region most common)
  15. perhexiline
    • 100mg d
    • Load: 200-300mg for 5-7d
    • TDM drug - slow metabolisers = very low doses, test after 3-5 days, MM kinetics
    • diabetes - hypos risk
    • P neuropathy
    • monitoring: weight, BSLs, hepatotoxicity, p neuropathy, levels
  16. Perindopril
    5-10mg d

    • reduce dose in elderly/renal imp - 2.5mg
    • 30-60mL/min = 1d
    • 15-30mL/min = alt days
  17. Ramipril
    1 d (2.5-10) in 1-2 doses (BD for HF)
  18. Amlodipine
    2.5-5mg d (max 10)
  19. diltiazem
    • IR: 180-240mg d (3-4 divided doses)
    • CR: 180-360 d
  20. lercanidipine
    10-20 d
  21. nifedipine
    • IR: 20-40mg BD
    • CR: 20-30 D, max 90 D (angina) OR 120mg d (HTN)

    • Med box:
    • IR: 1 D (10/20)
    • CR: 1 BD (20/30/60)
  22. verapamil
    • IR: 160 BD-TDS
    • CR: 120-240 D-BD
  23. Atenolol (Noten, Tenormin, Tensig)
    25-100mg d
  24. bisoprolol
    10mg d (initially 1.25mg d and gradually titrate up)
  25. carvedilol
    1 D (3.125/6.25/12.5/25)

    • Maintenance:
    • 25mg bd (max if <85 kg)
    • 50mg bd (max if >85kg)
    • initially 3.125mg BD and titrating up at intervals of at least 2 weeks
  26. Metoprolol (Betaloc, Minax)
    • 50-100mg D-BD (HTN, migraine)
    • 50-100mg BD-TDS (Angina)
    • CR: 23.75mg-190mg D (maintenance)
  27. propranolol
    • 120-320mg d (in 3 divided doses) (HTN, angina, tremor)
    • initially 20-40mg bd - tds
  28. Prazosin (Minipress)
    • 3-20mg D (in 2-3 divided doses)
    • initially 0.5mg BD
  29. Clonidine (Catapres)
    • po: 150-300mg BD (MD) (HTN)
    • 25mg BD, max 75mg BD (menopausal flushing)

    • withdrawal syndrome - risk of rebound hypertension, withdraw gradually over at least 7 days
    • withdrawal may worsen wtih BB. Stop BB days before removing clonidine
    • depression - may exacerbate, avoid
    • Common: sedation, depression, constipation, othostatin
  30. Hydralazine (Alphapress)
    • 50-200mg D
    • initially 25mg BD, caution with doses > 100mg D

    • arterial vasodilator
    • give 300mg D in 4 divided doses with ISDN (HF)
    • usually add BBS and thiazides to prevent tachycardia and fluid retention
    • Common sfx: oedema, flushing, tachycardia
  31. Amiodarone
    • 100-400mg D
    • use lowest MD to control arrhythmia
    • Loading required: po schedule: 200-400mg tds for 1 week, then 200-400 BD for 1 week

    • iodine allergy = C/I
    • monitor q6m: Thyroid fn, Lung fn (CXR), EUC (hypo/hyperK, hypoMg)
    • eye exam anually
    • counselling: sun exposure, regular tests, tell dr if dyspnoea, dry cough, problems with vision, wt loss, muscle weakness, worsening of heart symptoms
  32. digoxin
    • 62.5-250mcg D
    • tailor dose according to renal fn, clinical resp, and levels

    • SS after 5 days
    • Rnage: 0.6-2.6nmol/L
    • toxicity: a --> n --> v
    • Common sfx: a, n, v, d, blurred VISION, confusion,
  33. flecainide
    50-100mg po BD, max 400mg D
  34. Pravastatin
    20-80mg D
  35. rosuvastatin
    5-20mg D

    max 40mg D (specialist supervision)
  36. Simvastatin
    10-80mg D (usually 40mg - existing/risk CAD)
  37. Fenofibrate
    • 145mg D
    • (Lipidil)

    • lower dose in renal imp:
    • 20-60mL/min = 96 mg D

    • TRIGLYCERIDES
    • MOA: PPAR-g activators - lower TG, inc HDL ( mod), variable LDL effects
    • Common ADR: GI (dyspepsia, abdo pain)
    • infrequent: photosensitivity
    • monitor LFTs
  38. Ezetemibe
    10mg D

    • Reduces absorption of cholesterol (dietary and biliary) by inhibiting its transport across the intestinal wall = inc. LDL uptake
    • Tell GP if muscle pain, tenderness or weakness
    • Fibrate tx - increase risk of GALL BLADDER disease
    • Common ADR: headache, diarrhoea
  39. Felodipine
    1 D (2.5/5/10)

    • Plendil ER
    • Felodur ER
  40. Enalapril
    1 D (mane) (2.5/5/10/20)

    • AMH:
    • usu 10-40mg D (HTN) as 1-2 doses
    • 10-20mg D (HF) as 1-2 doses

    Renitec
  41. Captopril
    25-50mg TWICE daily

    Capoten
  42. Lisinopril
    1 D (mane) (5/10/20)

    Prinivil
  43. Fosinopril + HCT
    1 D (F: 10/20, HCT: 12.5)

    Monoplus, Fosetic
  44. Quinapril
    1 D (5/10/20)

    • Maintenance:
    • 10-40 D (mane) (in 1-2 doses) (HTN)
    • 5-10 D (HF)
    • 2.5-5 D (elderly/renal imp/taking diruretic)

    Accuretic, Accupril, Acquin
  45. Indapamide
    • IR: 1.25-2.5 D (mane)
    • CR: 1.5 D

    Risk of hypoK lower with CR tablet
  46. Trandolapril
    1 D (usu 1-2mg D, max 4mg D)

    Gopten
  47. Aspirin
    100-150mg D (anti-platelet)

    300-900mg D (analgesic)
  48. Rivaroxaban
    10mg D (2 weeks TKR, 5 weeks THR)

    • Factor Xa inhibitor (selective) - blocks thrombin production, conversion of fibrinogen to fibrin, and thrombus development
    • No antidote
    • Common ADR: bleeding, signs of bleeding (e.g. anaemia)
    • Oral (fondaparinux = sc)
  49. Dabigatran
    • 110mg BD
    • 150mg D (CrCl 30-50mL/min)

    • Direct thrombin inhibitor
    • 10 days after TKR, 4-5 weeks (28-35 days) after THR
    • lower dose (150mg) with amiodarone and conventional verapamil (or 2 hrs before Verapamil to avoid interaction)
  50. Iron tablets
    • 1mg elemental iron =
    • ferrous fumarate 3mg
    • ferrous sulphate (dried) = 3mg
    • ferrous sulphate (non-dried, heptahydrate) = 5mg

    • EMPTY STOMACH (1 hr b4/2 hrs after)
    • Shortly after food if upset stomach
    • Minimise GI sfx by: slowly inc dose, use CR (may have lower F)
    • accidental overdose serious - v, d, hypotension, tacchycardia, acidosis, CNS depression.
  51. Systemic photosensitisers
    • amiodarone
    • griseofulvin
    • NSAIDs
    • phenothiazines (chlorpromazine, pimozide, clozapine, promethazine, etc. - 'z-drugs')
    • methoxsalen (for psoriasis)
    • quinolones (ciprofloxacin, moxifloxacin, norfloxacin, ofloxacin)
    • retinoids (acitretin, adapalene, isotretinoin, tazarotene, tretinoin)
    • SJW
    • tetracyclines (doxycycline, minocycline, tetracycline)
    • thiazides (rare)
  52. Topical sensitisers
    • triclosan
    • coal tar derivatives
    • fragrances
    • methoxsalen
    • retinoids (adalaplene, isotretinoin, tazarotene, tretinoin)
    • sulfonamides
  53. topical corticosteroids
    • BD except for mometasone and methylprednisolone, which are applied ONCE a day
    • no benefit from more frequent application, some cases less may be adequate (e.g. eczema)
    • Dose = finger tip unit; tip of index to first crease: area twice size of adult hand with fingers together
    • Apply enough to cover affected areas. Smooth gently into skin, preferably after bathing
  54. hydrocortisone
    • 0.5-1%
    • mild
    • DermAid, Cortic-DS, Cortef, Sigmacort
  55. betamethasone valerate
    • 0.02%, 0.05%
    • moderate
    • 0.02% Betnovate 1/5, Cortival 1/5, Celestone-M
  56. desonide
    • 0.05%
    • moderate
  57. triamcinolone
    • 0.02%
    • moderate
    • Aristocort, Tricortone
  58. betamethasone dipropionate
    • 0.05%
    • potent
    • Diprosone, Eleuphrat

    very potent = diprosone OV
  59. betamethasone valerate 0.1%
    • 0.1%
    • potent (vs. 0.05% and less = moderate)
    • Betnovate, Cortival
  60. mometasone
    • 0.1%
    • potent
    • Elocon, Novasone
  61. methylprednisolone
    • 0.1%
    • potent
    • Advantan
  62. Isotretinoin
    • 0.5mg/kg d (as 1-2 doses)
    • treatment continued until total cumulative dose is 120-150mg/kg (usually 4-5 months)
    • Roaccutane, Oratane

    • PPs:
    • with food
    • promptly report n, headaches, visual changes (poor night vision or blurring)
    • dry lips, mouth, eyes - vaseline, lubricating eye drops. tell dr if not mgeable
    • avoid vit A supplements
    • photosensitivity - physical barrier sunscreen
    • Cat X - contraception during and for 1 month after
    • monitor BSLs in pts predisposed to diabetes

    ADRs: hyperlipidaemia, tetracyclines - inc risk of benign intracranial HTN, photosensitising meds, topical retinoids
  63. Permethrin
    • 1% - head lice
    • 5% - scabies: adult - 1 tube/application, 5-12 yrs - 0.5 tube, 1-5 yrs - 0.25 tube

    • scabies - apply chin-down and wash off with warm soapy water 8-14 hours later. rinse thoroughly. rpt after 7 days.
    • also apply to neck, face, scalp and ears in children <2 yrs, elderly or immunocompromised ppl, tx failure

    head lice: apply to damp hair after washing with usual shampoo, leave in for 10 mins, rinse with warm water, rpt after 7/7. Use fine tooth comb to remove dead lice/nits.
  64. Intranasal corticosteroids
    • 2 sprays D - acute phase
    • 1 spray D - MD

    • Beclomethasone 50mcg/dose - Beconase Allergy & Hayfever (use BD)
    • Budesonide 32mcg/dose - Rhinocort Hayfever; 64mcg/dose - Budamax, Rhinocort
    • Fluticasone 27.5mcg/dose - Avamys, 50mcg/dose - Beconase Allergy & Hayfever 24 hour
    • Mometasone 50mcg/dose - Nasonex
    • Triamcinolone 55mcg/dose - Telnase
  65. Glibenclamide
    2.5-20mg D (1-2 divided doses)

    Daonil, Glimel
  66. Gliclazide
    • IR: 40-320mg D (1-2 divided doses, max 160mg/dose)
    • CR: 30-120mg D

    NB: 30mg CR = 80mg IR

    Diamicron, Glyade
  67. Glimepiride
    1-4mg D

    Amaryl, Aylide
  68. Glipizide
    2.5-40mg D (1-2 doses - divide doses > 15mg)

    Minidiab
  69. Pioglitazone
    15-30mg D (max 45mg D)

    Actos
  70. Rosiglitazone
    4mg D (max 8mg D in 1-2 doses)

    Avandia
  71. Sitagliptin
    • 100mg D
    • reduce dose in renal imp
    • 25mg, 50mg, 100mg tabs av

    Januvia

    DPP-1 inhibitor (gliptin)
  72. Acarbose
    50mg D-TDS swallowed whole with liquid immeidately before a meal or chew with first few mouthfuls of food

    Glucobay
  73. Exanitide
    5mcg BD (10mcg BD if tolerated) - 60 mins before breakfast and dinner

    • GLP-1 analogue
    • Byetta
  74. Metformin
    • IR: 500-850mg D-TDS according to response (Max 3g D)
    • CR: 500mg-2g D (with evening meal)
    • Reduce dose in renal imp:
    • 60-90mL/min - 2g D
    • 30-60mL/min - 1g D
  75. Thyroxine
    • usual: 100-200mcg D
    • start at 25-50mcg, increase according to TSH
  76. Carbimazole
    • initially 20-40mg D (up to 60mg in severe cases) for 3-4 weeks
    • MD: 5-15 mg D

    • Neo-Mercazole
    • common: itching & mild rash --> antihistamines
    • rare: agranulocytosis - rapid onset in 1st 3 months -->tell dr stat: fever, mouth ulcers, sore throat, rash, severe fatigue, abdominal pain, jaundice
  77. Calcium
    1200-1300mg (including diet)

    • Dietary intake (Australian recommendations):
    • 1300mg - men >70, post-menopausal women, adolescents 12-18 yrs
    • 1000mg for all other adults
  78. Fosamax combinations
    • Fosamax Plus Once weekly 70/70 OR 140: alendronate 70mg, cholecalciferol 70mcg OR 140mcg
    • Fosamax Plus D-Cal: alendronate 70mg, cholecalciferol 140mcg (4), calcium 500mg (48)
  79. alendronate
    • 70mg once weekly OR
    • 10mg D
    • avoid use if CrCl <35mL/min
    • combination pack with:
    • cholecalciferol 70mcg OR 140mcg - 1/week (Fosamax plus 70/70 OR 70/140)
    • cholecalciferol 140mcg (w/ alendronate) & calcium 500mg (Fosamax plus D Cal)
  80. Actonel combinations
    • Actonel Combi: risedronate 35mg (4), calcium 500mg (24)
    • Actonel Combi D: risedronate 35mg (4), calcium 1000mg, cholecalciferol 22mcg (24)
  81. risedronate
    • 5mg D OR
    • 35mg weekly OR
    • 150mg monthly
    • not recommended if CrCl < 30mL/min
    • Actonel
  82. calcitriol
    0.25mcg BD

    (0.75mcg D when for OP prev'n w/ oral pred dose >10mg D)

    Rocaltrol
  83. Cholecalciferol
    • 25mcg D
    • 75-125 (3-5) daily for 6-12 weeks as loading dose
  84. raloxifene
    60mg D

    • Evista
    • SERM - oestrogen agonist effects on bone, antagonistic effects at other oestrogen-responsive tissue (e.g. breast, endometrium)
  85. Strontium
    2g D (bedtime, at least 2 hrs after food) - sachet, mix with water

    Rare ADR: VTE, DRESS (drug rash with eosinophilia) --> rash = seek advice promptly

    Protos
  86. chloramphenicol
    • Bacterial conjunctivitis:
    • 0.5% eye drop: 1 drp q2-4h for 2 days, then if there is improvement, 1 drop qid for 5 days
    • 1% ointment: use n as adjunct to eye drop, or as single agent TDS, e.g. in children

    • Prevention of infection after sx/superficial trauma:
    • 0.5% drop: 1 drop qid until epithelium healed (rarely > 4 days)
    • do not supply OTC if eye is red and painful (esp. if contact lens wearer) - further investigation req'd
  87. drug classes for chronic open-angle glaucoma - usual doses/day
    • BB (e.g. timolol) --> 1-2
    • PG analogue (e.g. latanoprost) --> 1
    • Carbonic anhydrase inhibitor --> 2 (except dorzolamide when single agent --> 3)
    • A2 agonist (e.g. brimonidine) --> 2
    • cholinergic (e.g. pilocarpine) --> 2-4
  88. MOA of glaucoma eye drops
    • BBs - dec aqueous humor formation
    • PG analogues - inc UV scleral outflow
    • A2 agonist - dec aq humor formation and inc UV scleral outflow
    • CA-i - dec aq humor formation
    • ie. dec aq humor formation - all classes except PG analogues, A2 agonists - do both (2 for both!)
  89. Preferred H. Pylori eradication regimen
    • PPI - standard dose BD
    • clarithromycin 500mg BD
    • amoxycillin - 1g BD
    • duration: 7 days
  90. H. Pylori eradication regimen if amoxycillin unsuitable
    • PPI - standard dose BD
    • clarithromycin - 500mg BD
    • metronidazole - 400mg BD
    • duration: 7 days
  91. H. Pylori eradication regimen if clarithromycin unsuitable
    • PPI - standard dose BD
    • amoxycillin - 500mg TDS
    • metronidazole - 400mg TDS
    • duration: 14 days
  92. ranitidine
    300mg daily (1-2 divided doses)
  93. esomeprazole
    Usually 20mg D-BD (range: 20-40mg D-BD)

    • tablet - swallow whole or dispserse in water and drink within 30 mins
    • oral liquid/sachet av

    Nexium
  94. lansoprazole
    15-30mg D

    • capsule - open and mix with juice/yogurt
    • tablet - suck, swallow whole with water, disperse and drink stat

    Zoton
  95. omeprazole
    MD: 10-20mg D

    Losec, Acimax
  96. pantoprazole
    20-40mg D

    somac
  97. rabeprazole
    10-20mg D

    Pariet
  98. Hyoscine butylbromide
    • 10-20mg TDS-QID
    • doses can be repeated after 30 mins prn

    • MOA - SM relaxant, dec GI motility
    • Indications: GI spasm, aid in endoscopy, IBS

    buscopan, setacol
  99. mebeverine
    135mg TDS

    • MOA: SM relaxant, reduces GI motility and spasm
    • indications: IBS

    Colese, Colofac
  100. domperidone
    10-20mg TDS -QID

    • n+v, gastroparesis: 10-20mg q6-8h (TDS-QID) (max 80mg D) (12 weeks - n+v, 6 months - gastroparesis)
    • stimulation of lactation: 10mg TDS for 5 days, then taper down

    • prolongs QT interval - C/I with ketoconazole, erythromycin and other potent inhibitors of CYP3A4 (e.g. fluconazole, clarithromycin)
    • ADRs: dry mouth (common), hyperprolactinaemia --> boobs, leaking (infrequent), EPSE (rare)

    Motilium
  101. metoclopramide
    10mg TDS

    • n+v, gastric stimulation, lactation stimulation
    • caution - PD (prefer domperidone) - EPSE, depression + elderly - avoid LT use

    dopamine ANTagonist
  102. Prochlorperazine
    • n+v: initially 20mg, then 10mg 2 hrs later
    • if still needed, 5-10mg TDS PRN

    potentiates CNS dep - C/I

    • ADR: common: constipation, dry mouth, drowsiness, parkinsonism, EPSE (esp children), hyperprolactinaemia
    • rare: prolong QT

    counselling - L1: drowsy, EtOH

    • Nausetil, Stemetil, Stemzine
    • 5mg tabs, 25mg suppositories
  103. hyoscine butylbromide
    1-2 tabs, max 4/24 hrs (halve dose in children)

    • 1 tab = 0.3mg = 300mcg
    • take 1st dose 30 mins before travel, repeat in 4-6 hrs prn
    • indication: motion sickness
    • Kwells, Travacalm HO
    • combination: Travacalm original (hyoscine butylBr 0.2mg. dimenhydrinate 50mg, caffeine 20mg)
  104. docusate
    100-150mg D-BD (max 480mg D)

    onset 1-3 days (po)
  105. lomotil, lofenoxal
    2 TDS-QID PRN

    diphenoxylate 2.5mg (+ atropine 25mcg)

    L1 - drowsiness, alcohol
  106. Imodium, Gastro-Stop
    acute diarrhoea, SHORT TERM: initially 4mg, then 2mg after each loose bowel motion (max 16 mg D)

    loperamide 2mg
  107. Imodium advanced
    loperamide 2mg, simethicone 125mg

    diarrhoea associated with gas-related abdominal discomfort, SHORT TERM
  108. Oral rehydration salts
    • 2 tabs or 1 sachet into 200mL fresh drinking water/freshly boiled and cooled water
    • Age determines dose:
    • 6-24 months: 1 sachet/q3-4h
    • 2-5 yrs: 1-2 sachet/q3-4h
    • 5-8 yrs: 2 sachet/q3-4h
    • 8-10 yrs: 1 sachet/q1-2h
    • 10-12 yrs: 1 sachet/q1h (up to 6-12 sachets in 24h)
    • adults, children >12y: 1-2 sachets after every loose bowel motion (up to 8-12 sachets in 24 hrs)

    • seek medical advice if diarrhoea persists:
    • <6 months: >6 hrs
    • <3 yrs: >12 hrs
    • 3-6 yrs: > 24 hrs
    • 6+ yrs: >48 hrs

    • Reconstituted soln can be stored for up to 24 hrs in FRIDGE, otherwise d/c w/in 1 hr
    • If vomitting - drink in small amounts at first
  109. colifoam
    1 applicatorful D-BD for 2-3 weeks, then every second day until remission achieved

    • indications: UC, CD; mild rectal/rectosigmoidal disease
    • hydrocortisone 10% - rectal foam
  110. 5-ASAs - agents
    • balsalazide - Colazide
    • mesalazine - mesasal, salofalk, pentasa
    • olsalazine
    • sulfasalazine - salazopyrin (contains sulfonamide moiety)
    • monitoring: renal and liver fn - baseline, q3m for 1 yr, then q6m
  111. sulfasalazine
    • Acute: 2-4g D in 3-4 doses (UC), 3-6g D (CD)
    • MD: 500mg QID
    • RA: initially 500mg D (max 3g), MD: 2-3g D
    • C/I - allergy to sulphonamides, blood dyscrasias
    • common sfx: reversible male infertility, haemolysis (usu not severe)
    • take WITH FOOD
    • STAINS - urine - dark orange, skin & tears - yellow, soft contacts - stained
    • impairs absorption of FOLIC ACID (NB: sulfonamide moiety)- consider supplements
  112. xenical
    • 120mg TDS with main meals
    • Do not take dose if you miss a meal/meal dose not contain fat
    • likely to cause fatty or oily stools, esp when diet too high in fat
    • efficacy for up to 4 yrs
    • mean wt loss of approx 2-4 kg in 1st yr
    • may decrease abs of fat-sol vitamins (ADEK) - supplement if necessary at least 2 hrs from orlistat dose
    • orlistat
  113. oxybutinin
    • oral: 2.5-5mg BD-TDS (max 20mg D) (Ditropan)
    • patch: 1 patch TWICE weekly (q3-4 days) - apply to abdomen, hip or buttock; patch = 3.9mg/24hrs (Oxytrol)
    • anticholinergic
    • urinary urge incontince
  114. solifenacin
    • 5-10mg D
    • anticholinergic
    • urinary urge incontinence
    • Vesicare
  115. selective alpha-blockers - agents + MOA
    • alfuzosin
    • prazosin
    • tamsulosin
    • terazosin

    MOA: block A1 receptors, relaxing SM in bladder neck, decreasing resistance to urinary flow

    • tamsulosin most selective
    • less effect on BP: tamsulosin, alfuzosin - better tol
    • prazosin - short duration of action - BD

    • precautions:
    • intra-operative floppy iris syndrome during cataract sx (esp tamsulosin)
    • first dose hypotension
  116. Prazosin in BPH
    0.5-2mg BD

    Minipress
  117. tamsulosin
    400mcg D

    flomaxtra
  118. finasteride
    5mg D

    indications: BPH, alopecia in men

    Proscar
  119. celecoxib
    • 100mg D-BD, max 400mg D
    • Do not use >200mg D LT - risk of CV ADR dose-related

    Celebrex
  120. Diclofenac
    • 75-150mg D in 2-3 divided doses (max 200mg D) (po)
    • 1-2 TDS PRN (25)

    1% gel - rub into affected area BD - TDS PRN
  121. Ibuprofen
    200-400mg TDS-QID PRN (max 2400mg D)

    Nurofen, Panafen, brufen, advil

    NB: ibuprofen can reduce the antiplatelet activity of low-dose aspirin, possibly reducing or negating its cardioprotective effect - consider if using LT
  122. Indomethacin
    • po: 25-50mg BD-QID
    • pr: 100mg D-BD

    Indocid, Arthrexin
  123. Meloxicam
    7.5-15mg 1 D PRN

    Mobic, Movalis
  124. Naproxen
    • IR: 250-500mg BD
    • CR: 750-1000mg D
    • max, 1250mg D

    period pain: 500mg initially, then 250mg q6-8h prn

    NB: naproxen may reduce/negate cardioprotective effects of low-dose aspirin

    CR products - take nocte to reduce nocturnal and morning sx

    Inza, Naprosyn, Naproxyn SR
  125. azathioprine
    • 1mg/kg D (usually 50-100mg D in 1-2 doses)
    • MD: 50-150mg D (1-2 doses)

    Allopurinol reduces AZA metabolism = inc risk of severe BM toxicity. Redue AZA dose to a QUARTER or a THIRD of normal dose.

    Referal: persistent fever, sore throat, bruising, bleeding, paleness

    Imuran
  126. Methotrexate
    5-25mg once weekly, depending on response

    referal: cough, difficulty breathing, signs of infection

    photosensitivity

    • monitor: FBC, Hep B + C serology, pulmonary fn tests + CXR
    • GI ADRs:
    • folic acid supplements - 1mg D to reduce GI ADRs (stomatitis, nausea, diarrhoea)
    • divide oral dose into 3 - take at 0, 12, 24 hrs
    • may be 1-2 months before effect seen
  127. Hydroxychloroquine
    • RA: 2-3 (200mg) D for 1-3 months
    • MD: 1-2 D (if desired/responsive)

    malaria p'laxis: 400mg once weekly (start 1 week before leaving and 4 weeks after leaving endemic area)

    • MOA: anti-inflammatory + immunosuppressive effects
    • Indications: mild RA, malaria prophylaxis of chloroquine not available (reasonable 1st choice in mild disease)

    ADRs: retinopathy (rare) - tell dr if any changes in sight, wear sunglasses - VISION!
  128. sulfasalazine (RA)
    • 500mg D (inc to max of 3g D)
    • MD: 2-3 g D

    • with food
    • monitor: FBC, renal and liver fn tests
    • 1-3 months for effect
  129. allopurinol
    • 100-300mg D
    • prevention of hyperuricaemia due to tumour lysis syndrome: 600-800mg D

    • MOA: inhibits xanthine oxidase = dec uric acid production
    • after food
    • stop + see Dr: rash, swollen lips or mouth, persistent fever, sore throat
    • drink lots of fluids - prevent kidney stones
    • L1 - drowsy
    • interaction with azathioprine/mercaptopurine - reduce their dose to a QUARTER to a THIRD normal dose
    • consider low-dose NSAID/low-dose colchicine to prevent gout during 1st 3 months of tx

    • Progout
    • zyloprim
  130. colchicine
    • tx: 1mg ASAP, then 500mcg 1hr later (max 1.5mg/course)
    • prophylaxis: 500mcg D-BD

    MOA: inhibits neutrophil activity - reduces inflammatory reaction to urate crystals (no effect on uric acid)

    common ADR: GI (n, v, d, abdominalk discomfort)

    Dr: severe v/d, myalgia, peripheral neuropathy, unusual bleeding, infection

    accumulation and toxicity if used with CYP3A4 inhibitor (e.g. clarithromycin), or course repeated too quickly

    Colgout, Lengout (500mcg tabs)
  131. topical muscoloskeletal agents
    • Apply BD - QID PRN for up to 14 days, r/v use afterwards
    • may stain skin and discolour skin - rub in properly
    • photosensitivity
    • rice for days 1-2
  132. carbamazepine
    • Epilepsy:
    • usual range = 400-1.2g D (in 2 + doses) (max 3g D)
    • initially 100mg BD and titrate up

    • neuropathic pain: 200-600mg BD
    • mania/bipolar: 400mg D (divided doses), titrate up to effect

    th range: 4-12mg/L

    • MOA: prevents repetitive neuronal discharge by blocking
    • voltage and use-dependent Na channels

    • Indications:
    • - partial seizures (simple and complex), generalised tonic-clonic
    • - bipolar - acute mania and prevention
    • - neuropathic pain

    • Increase dose slowly - auto-induces own metabolism monitor for life-threatening skin reactions
    • risk of osteomalacia - vit D + cal supp's

    Tegretol
  133. CBZ (in epilepsy)
    400mg - 1.2g D (in 2-4 divided doses) (max 2g D)

    Tegretol
  134. CBZ
    • In 2-4 doses:
    • 400mg - 1.2g D, max 2g (epilepsy)
    • 400-800mg D, max 1.6g (trigeminal neuralgia)
    • 200-600mg D, max 1.2g (neuropathic)
    • 400mg D, max 1.6g (mania/bipolar)
    • Tegretol
  135. Gabapentin
    • partial seizures: usually 0.9-1.8g D (in 3 divided doses)
    • neuropathic pain: 1.8-3.6g D (in 3 divided doses), but initially 100-300mg nocte

    • L1 - drowsiness, EtOH
    • L9 - do not stop abruptly

    Neurontin
  136. Lamotrigine
    • 100-200mg D (in 1-2 doses)
    • (OR 200-400mg D (in 2 doses, up to 500-700mg D) in pts taking enzyme inducers and not taking valproate)

    ADR: common: VISION (diplopia, blurred vision), dizziness, somnolescence; SEVERE SKIN REACTIONS - occur with rapid dose inc/valproate tx

    Lamictal, Seaze
  137. Levetiracetam
    500mg BD, up to 1.5g BD (adults, children > 50kg)

    Keppra
  138. Phenytoin
    usually 200-500mg D (in 1-2 doses)

    not effective in absence and myoclonic seizures

    • ADRs: VISION (diplopia, blurriness), gingival hypertrophy - visit dentist regularly
    • TDM - total PHY = 40-80mmol/L
    • saturable metabolism/MM kinetics

    Dilantin
  139. pregabalin
    75-150mg BD (max 300mg BD) (partial seizures + neuropathic pain)

    Lyrica
  140. Valproate
    epilepsy: 600mg D (in 2 doses) titrate to response, max 2.5g D

    • common ADR: increased appetite, wt gain, elevated ALT/AST, blood dyscrasias --> fever, rash, abdo pain, bruising, bleeding (inc INR/thrombocytopaenia)
    • BMD - monitor/supplement vit D/Ca

    indications: epilepsy, migraine, bipolar

    Epilim (100, 200, 500mg)
  141. Drug classes for PD + common examples
    • Levodopa
    • DOPA-decarboxylase - carbidopa, benserazide (given with levo) - decreases peripheral metabolism of levo (= less n, v, hypotension)
    • MAO-B inhibitor - selegeline (levo adjunct)
    • COMT-i - entecapone (levo adjunct)
    • dopamine agonists - pramipexole (non-ergot), carbergoline
    • apomorphine - stimulates dopa Rs, use with domperidone (highly emetogenic)
    • Amantadine - dopaminergic and anticholinergic activity
    • anticholinergics - benzhexol, benztropine, etc. - used infrequently
  142. Entacapone
    200mg with each levodopa/carbidopa or benserazide dose (max 2 g D)

    • COMT-I
    • indications: adjunct to levo with motor fluctuation

    Comtan (200mg)
  143. levodopa with benserazide or carbidopa
    dosage expressed as levo: 50-100mg TDS, titrate to response (max 2g D)

    levodopa : benserazide/carbidopa = 4:1, 10:1 ratio also av with carbidopa

    do not stop suddenly, take at same time daily and same way (with/without food - food reduces abs of levo, but minimised GI fx)

    • w/ Benserazide
    • Madopar (50-200mg levo) rapid (tab)
    • Madopar (50-200mg levo) (cap)

    • w/ Carbidopa
    • Sinemet, Kinson (100-250mg levo)
    • Sinemet CR (200mg levo)

    • w/ Carbidopa + Entecapone
    • Stalevo (50-200mg levo) + 200mg entecapone
  144. Sumatriptan
    • 50-100mg ASAP after headache onset
    • MOA: constrict cranial vessels (selective 5HT1B/D) - C/I in IHD, TIA
    • indications: acute relief of migraine
    • take as headache beginning to develop; if no improvement with first dose, do not repeat; repeat after at least 2 hrs if migraine recurs
    • Imigran, Sumagran
  145. Donepezil
    • 5-10mg D (bedtime)
    • Anticholinesterase
    • Aricept
  146. Galantamine
    • 8-16mg D (mane, max 24mg)
    • anticholinesterase
    • Reminyl, Galantyl
  147. levonorgestrel + ethinyloestradiol
    • 100mcg levo, 20mcg ED - microgynon, loette, microlevlen
    • 150mcg levo, 30mcg - microgynon, levlen, monofeme, nordette
  148. Oestradiol
    monorest, femtran, estraderm, climara
  149. standard doses of SSRIs
    • 10mg escitalopram
    • 20mg citalopram, fluoxetine, paroxetine
    • 50mg sertraline
    • 50-100mg fluvoxamine

    dose may be higher in OCD or eating disorders (vs. for depression or anxiety)
  150. citalopram
    20mg D (max 60mg)

    Cipramil
  151. Escitalopram
    10mg D (max 20mg D)

    Lexapro
  152. Fluoxetine
    20mg D (max 60mg D)

    longer t1/2

    Lovan, Prozac
  153. Fluvoxamine
    50mg D, titrate to effect (max 100-300mg D)

    nocte of somnolence exp'd

    Luvox, Movox
  154. Paroxetine
    20mg D (max 50mg D)

    short t1/2 - more likely to exp withdrawal fx

    Aropax
  155. Sertraline
    50mg D (max 200mg D)

    Zoloft, Eleva
  156. amitriptyline
    • depression: 75-150mg D (max 300mg D)
    • pain mgt, migraine p'laxis: 10-25mg N (max 75 in migraine, 150mg pain)
    • Urge incontinence: 10-25mg D-TDS
    • Endep
  157. TCAs - dose in major depression
    75-150mg D (max 300mg D, except nortriptyline - max 150mg D)
  158. TCAs indicated in things other than depression
    • amitriptyline, nortriptyline, imipramine - nocturnal enuresis, urge incontinence
    • (amitriptyline also indicated for pain mgt, migraine p'laxis)
  159. Dothiepin
    75-150mg D (max 300mg)

    Prothiaden, Dothep
  160. Nortriptyline
    • maj depression: 75-150mg D (max 150mg)
    • nocturnal enuresis: 10-20mg nocte
    • urge incontinence: 10-25mg D-TDS
    • Allegron
  161. Desvenlefaxine
    50mg D (max 200mg D)

    • major metabolite of venlefaxine
    • SNRI

    Pristiq
  162. duloxetine
    30-60mg D

    • SNRI
    • indications: major depression, GAD, painful diabetic peripheral neuropathy

    Cymbalta
  163. Mirtazapine
    15-45mg nocte (max 60mg)

    • tetracyclic antidepressant
    • post-synaptic blockade of 5HT2 & 3 Rs, presynaptic blockade of central A2 autoRs

    Axit, avanza, mirtazon
  164. moclobemide
    450-600mg D (in 1-2 doses, usual max 600mg D)

    • indications: depression and anxiety
    • selective MAO-A-i - inc presynaptic conc's of 5HT, dopamine, NA - take doses no later than early afternoon
    • low tyramine diet not required

    aurorix
  165. venlefaxine
    75-150mg D, sometimes 225mg (max 300mg)

    hypertension - may be exacerbated, monitor BP when starting

    Efexor
  166. monitoring for antipsychotics
    • weight
    • blood gluclose
    • BP
    • lipids
    • FBCs
    • LFTs
  167. chlorpromazine
    • AP: 25-100mg TDS - QID (max 1000mg D)
    • acute beh dist: 50-100mg q2h PRN (max 500mg D)

    indications: antipsychotic, ST mgt of anxiety/agitation/disturbed beh, intractable hiccup

    ADR: photosensitivity, contact dermatitis on contact with soln

    largactil
  168. clozapine
    usually 200-600mg D (max 900mg)

    monitoring: neutrophils, WBCs

    caffeine and smoking - affect dose

    Clopine
  169. Haloperidol
    • chronic psychoses: 1-5mg BD-TDS (max 30mg D); 0.5-10mg D in elderly (EPSE)
    • acute psychoses and mania: 5-10mg q2h PRN

    indications: acute and chronic psychoses. acute mania, severe anxiety/agitation/beh disturbance

    Serenace
  170. Olanzapine
    • schizophrenia: 10-20mg D
    • acute mania and MD in bipolar: 2-20mg D

    indications: schizophrenia, bipolar (adjunct to Li/valproate)

    • common ADR: hyperglycaemia, T2DM, wt gain, p oedema, constipation
    • EPSE infrequent

    Smoking - affect levels

    Zyprexa
  171. Quetiapine
    300-800mg D, lower doses generally required for bipolar than schizophrenia

    • schizophrenia:
    • IR: 150-800mg BD, usual effective dose 400-800mg BD
    • CR: 400-800mg D

    • bipolar:
    • IR: 300-800mg D (in 2 doses)
    • CR: 300-800mg D

    indications: schizophrenia, monotherapy/adjunct in bipolar (to lithium/valproate), adjunct in major depression

    • common: tachycardia, constipation, somnolescence
    • infrequent: inc ALT/ALP, wt gain, neutropenia

    Seroquel
  172. Risperidone
    • schizoprenia, bipolar (acute mania): usual range = 4-6mg D (po), 25-50mg q2weeks (im)
    • behaviour dist in demetia: 0.25-1mg BD

    Risperdal, Risperdal Consta (im)
  173. Lithium
    250-1000mg D (in divided doses - BD if CR product) (max 2500mg D)

    hyponatraemia (e.g. dehydration, low Na diet) - inc risk of toxicity

    toxicity = blurred vision, extreme thirst, frequent urination, n/v/d - tell pt!, esp during illness/excessive sweating/low fluid intake

    avoid urinary alkalinisers- decreases potency

    TDM: 0.4-1mmol (prophylaxis)

    monitoring: TSH, ECG, electrolytes, LFT, FBC

    • Lithicarb (250mg IR)
    • Quilonum (450mg CR)
  174. Alprazolam
    0.5-4mg D (max 10mg D - panic disorder)

    Kalma, Xanax
  175. Diazepam
    • depends on indication
    • anxiety, agitation, parasomnia: 1-10mg TDS PRN

    Valium, Antenex

    indications: ST mgt of anxiety, agiation, acute EtOH withdrawaal, muscle spasm, benzo withdrawal
  176. flunitrazepam
    0.5-2mg nocte

    Hypnodorm
  177. lorazepam
    1-4mg

    Ativan
  178. nitrazepam
    5-10mg nocte

    Alodorm, Mogadon
  179. oxazepam
    7.5-30mg nocte (3-4 times daily for anxiety)

    Serepax, Murelax
  180. temazepam
    5-20mg nocte

    normison
  181. zolpidem
    5-12.5mg nocte

    • Stilnox
    • 6.25mg, 12.5mg CR
    • 10mg IR
  182. zopiclone
    3.75-7.5mg nocte

    Imovane
  183. atomoxetine
    • approx 1mg/kg/day (1.2mg/kg) - give as a single dose mane, or m and late afternoon (max 100mg D)
    • MOA: inhibits presynaptic NA reuptake
    • ADHD
    • common: GI fx, inc BP, somnolescence, aggression
    • rare: suicidal thoughts/behaviours, hepatic dysfn
    • couselling: L1 + GP for signs of hepatotoxicity (yellowing of skin/eyes, dark urine, tiredness, pale faeces)
    • Strattera
  184. dexamphetamine
    • child: 2.5-10mg D
    • adult: 10mg m, titrate up to 60mg D (divided doses)
    • MOA: enhances dopaminergic and NA NT
    • indications: ADHD, narcolepsy
    • avoid taking doses after early afternoon
    • no brand
  185. methylphenidate
    • 5-40mg D in divided doses (unless LA prep) (max 60mg in adults)
    • 5-10mg daily, titrate to effect (max 40mg D) (<10mg D in 1-2 doses. >10mg D in 2-3 doses)
    • MOA: enhance NA and dopaminergic neurotransmission
    • indications: ADHD, narcolepsy
    • avoid taking doses after early afternoon
    • IR: ritalin
    • LA: Concerta, Ritalin LA
  186. acamprosate
    • adult >60kg: 2 tabs TDS
    • adult <60kg: 2 tabs m, 1 midi, 1 n
    • tablet = 333mg
    • MOA: reduces cravings, GABA analogue
    • indications: maintain abstinence in alcohol dependence
    • preferred when opiods used for pain
    • Campral
  187. disulfuram
    • MD: 200mg D (max 300mg D)
    • deters EtOH use - blocks acetylaledhyde - prevents usual metabolism of alcohol --> unpleasant effects if EtOH consumed (flushing, sweatgin , n+v, palpitations, dyspnoea, etc.)
    • indications: maintenance of abstinence
    • precautions: IHD (C/I), isoniazid and metronidazole inc's risk of toxic reactions
    • referral: jaundice sx, AVOID ETOH (inc. alcohol containing aftershaves, body lotions, vinegar, etc.) during tx and 7 days after
    • Antabuse
  188. naltrexone
    • 50mg once D
    • MOA: opiod antagonist - reduces cravings and pleasurable fx
    • adjust in tx and maintenance of abstinence
    • precautions: opiod tx, imp liver fn
    • monitor: LFTs (esp. bilirubin)
  189. bupropion
    • 150mg m (3 days), then 150mg BD for 7-9 weeks
    • 150mg m in elderly
    • take medication for at least a week before you stop smoking - takes this long for it to be effective
    • inhibits dopamine and NA reuptake
    • may exacerbate schizophrenia, dep, bipolar, seizure
    • ADRs: INSOMNIA, agitation, tremor, fever, rash, dry mouth, constipation, tachy (infreq.)
    • stop taking if not markedly helpful
    • Zyban
  190. nicotine - dose form choice
    • MI/unstable angina/IHD - do not use
    • GORD - avoid gum/lozenge
    • denture work - avoid gum
    • asthma - avoid use of inhaler
    • skin cond - avoid patch
    • pregnancy - short acting products preferred, remove patch at night if using
    • breastfeeding - short acting product after feed
    • ADRs: nicotine - sleep disturbance, vivid dreams (esp 24 hr patch), dizziness, wt gain, headache; lozenge/gum - irritation of throat, mouth, sinusitis; patch - redness, itch, rash
  191. nicotine - doses (high dependence)
    • Tx duration - 12 weeks (6-8 wks most ppl)
    • gum: 6-10 pieces of 4mg gum D, avoid >1 piece/hr; taper o/ 3months; each piece lasts about 30 mins, can be cut if too bulky/tapering dose, excessive chewing = salivation = indigestion
    • inhaler - 6-12 cartridges D (10mg)
    • lozenge: 1 q1-2h (max 15/24h for 2 and 4mg, 20/24h for 1.5mg) - dissolve in mouth, do not chew/swallow, try not to eat or drink with lozenge
    • patch: 1 D (stop w/in 12 wks)
    • s/l tab: 1-2 q1-2h (max 40 tabs/d) - apply to upper body
  192. varenicline
    • initially 0.5mg D for 3 dya, then 0.5mg BD for 4 days, then 1mg BD for 11 weeks (i.e. 12 week tx)
    • start 7-14 days before stopping
    • if successful in stopping smoking by the last week, consider reducing to 1mg m for the last 2 weeks, then stopping - (insomnia, craving by some after sudden stopping)
    • NO NRT!! - worsen n + headache
    • MOA: partial agonist at nicotinic Rs - reduces pleasurable fx of smoking and prevents withdrawal
    • precaution: psychiatric condition may be worsened; use w/ NRT - may inc. risk of NAUSEA, headache, dizziness, dyspepsia
    • Common: NAUSEA, sleep disorder, constipation
    • Champix
  193. buprenorphine
    • usu 12-24 mg D (start with 4mg s/l m; max 32 mg D)
    • MOA: partial opioid R agonist - reduces cravings and withdrawal symptoms
    • contraindicated if currently intoxicated - delay dose until resolved (will further depress respiration)
    • use non-opioid analgesics if possible/consider methadone
    • common: constipation, hypotension
    • opioids, methadone >30mg, alcohol, benzos (esp during start) - risk ppting withdrawal; give at least 6 hrs after last use (ideally when some sx of withdrawal present - usu 1-4hrs)
    • may be possible to admin double dose on alternate days
    • subutex (0.5, 2, 8mg tabs)
    • suboxone (2/0.5, 8/2mg) - ie: 4:1 ratio
  194. methadone
    • MD: 60-80mg D (12-16mL) (start at 20-30mg D)
    • C/I if currently intoxicated - further resp dep
    • ADR: prolong QT (rare, pot from high dose), drowsiness (start, dose inc.)
    • may take days to feel effects - don't use
    • higher than standard opioid doses for analgesia
    • Biodone
  195. eformoterol
    • 6-12mcg BD (max 48mcg D)
    • w/ Budesonide (symbicort)
    • MD: 1-2 BD
    • sx relief: 1 PRN (max 6), if sx recur (max 12)
    • Oxis
  196. salbutamol
    • 1-2 PRN or 5-15 mins before exercise
    • repeat TDS-QID as necessary, higher in exacerbations

    • 100mcg/dose MDI
    • 2.5mg, 5mg nebs

    Asmol, ventolin, airomir
  197. salmeterol
    50mcg BD (max 100mcg BD in severe disease)

    • combination with fluticasone (Seretide)
    • MDI (25mcg S) - 2 puffs BD (50, 125, 250mcg F)
    • DPI (50mcg S) - 1 puff BD (100, 250, 500mcg F)

    COPD: 50mcg BD

    • Serevent accuhaler (50mcg/dose)
    • Seretide (w/ F)
  198. Terbutaline
    • 500mcg PRN or 5-15 mins before exercise
    • rpt TDS-QID PRN

    acute: 4 puffs (repeat after 4 mins until ambulance arrives)

    Bricanyl (DPI, inj)
  199. ipratropium
    • MDI: 2 puffs (40mcg) TDS-QID PRN
    • neb: 250-500mcg TDS-QID PRN

    acute: MDI with spacer - 6 puffs (120mcg) OR 500mcg neb q2h WITH SALBUTAMOL

    • admin: dilute solution for nebulisation with 2-3mL saline
    • refer: eye pain/discomfort/halos

    • MDI: 20mcg/dose
    • neb: 250mcg, 500mcg

    Atrovent
  200. tiotropium
    18mcg via HandiHaler mane

    spiriva
  201. theophylline
    • MD: max 900mg D - dose deps on response and level
    • indications: maintenance in SEVERE asthma and COPD
    • TDM 10-20mg/L
    • with food
    • Nuelin SR (200, 250, 300mg tabs), syrup (50% sugar)
  202. prednisolone (for asthma)
    1mg/kg 1 D, then taper
  203. Budesonide
    • 100-400mcg BD (adult)
    • Pulmicort (DPI 100, 200, 400mcg/dose); neb 0.5mg, 1mg
  204. Fluticasone
    100-200mcg BD (refer when >800mcg D req'd)

    • Flixotide
    • Jr = 50mcg/dose
    • MDI = 125, 250mcg
    • DPI = 100, 250, 500mcg
    • neb = 0.5, 2mg
  205. codeine (for cough)
    15-30mg 3-4 times D
  206. dextromethorphan (for cough)
    • 10-20mg q4h OR 30mg TDS-QID (max 120mg D)
    • NB: Serotonin toxicity
  207. dihydrocodeine
    • 5-10mL q4-6h
    • Rikodeine
  208. pholcodeine
    • 10-15mg 3-4 times D
    • Duro-Tuss Dry (reg 1mg/mL; forte 3mg/mL)
  209. ADT booster
    diptheria and tetanus
  210. Dukoral
    cholera vaccine (oral)
  211. Boostrix
    diptheria, tetanus, pertussis vaccine
  212. Hiberix
    H influenzae type B vaccine
  213. Fluvax
    Influenza vaccine
  214. Priorix
    measles, mumps, rubella

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