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What are the hemoglobin chains in Hb Bart?
4 gamma chains
What are the hemoglobin chains in Hb H?
4 beta chains
gene deletion causes what thalasemia?
pt mutation causes what thalasemia?
which is more deleterious?
- Alpha thalasemia--more deleterious
- beta thalasemia--less deleterious
What are the conditions that produce Target cells i.e the 2 ends of RBC join producing a target cell appearance?
- Liver disease
What are the 2 conditions that produce basophilic stippling of RBC?
- Lead poisoning --ALA dehydratase
- Sideroblastic anemia-- ALA synthase
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