Familial Polyposis Syndromes

Card Set Information

Author:
Anonymous
ID:
105618
Filename:
Familial Polyposis Syndromes
Updated:
2011-10-01 18:34:46
Tags:
COMLEX
Folders:

Description:
GI, COMLEX
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  1. Hundreds of polyps in colon
    • Familial adenomatous polyposis
    • near-certain development of malignant neoplasm, prophylactic subtotal colectomy recommended
  2. Cancer arises from normal appearing mucosa, neoplasms tend to form in proximal colon
    Hereditary nonpolyposis colorectal cancer (HNPCC)
  3. Hundreds of polyps in colon, common bone and soft tissue tumors
    Gardner's syndrome
  4. Polyps which are hamartomas with low risk of malignancy, mucocutaneous pigmentation of the mouth, hands, and genitals
    Peutz-Jeghers syndrome
  5. Many colonic adenomas with high malignant potential, comorbid malignant CNS tumors
    Turcot syndrome
  6. Polyps of colon, small bowel, and stomach that frequently are a source of GI bleeding
    • Juvenile polyposis
    • slightly increased risk of malignancy later in life

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