quiz 2 - Phar 605

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VASUpharm14
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105703
Filename:
quiz 2 - Phar 605
Updated:
2011-10-02 13:14:09
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im too cool
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quiz 2 - outpatient lab top 200 - set 21-40
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  1. Flonase
    generic?
    fluticasone propionate (nasal)
  2. Flonase
    class?
    antiallergy agent
  3. Flonase
    MOA?
    steroid binds and cause synthesis of specific enzymes to carryout antiallergy and anti-inflammatory actions.
  4. Flonase
    dosage form?
    Spray
  5. Lexapro
    generic?
    escitalopram oxalate
  6. Lexapro
    class?
    antidepressant
  7. Lexapro
    MOA?
    • S-enantiomer of citalopram
    • serotonin reuptake inhibitor blocking neuronally (human platelets in CNS).
  8. Lexapro
    dosage form?
    • Tablets (5, 10, 20 mg)
    • Oral solution (5 mg/5mL - peppermint flavor)
  9. Ultram
    generic?
    tramadol hydrochloride
  10. Ultram
    class?
    analgesic
  11. Ultram
    MOA?
    • bind to m-opioid receptor and inhibit reuptake of NE and serotonin
    • M1 metabolite form - 6x potent in producting analgesia
  12. Ultram
    dosage form?
    Tablets (50 mg)
  13. Ultram ER
    generic?
    tramadol hydrochloride
  14. Ultram ER
    class?
    analgesic
  15. Ultram ER
    MOA?
    • bind to m-opioid receptor and inhibit reuptake of NE and serotonin
    • M1 metabolite form - 6x potent in producing analgesia
  16. Ultram ER
    dosage form?
    Tablets (extended-release - 100, 200, 300 mg)
  17. Ryzolt
    generic?
    tramadol hydrochloride
  18. Ryzolt
    class?
    analgesic
  19. Ryzolt
    MOA?
    • bind to m-opioid receptor and inhibit reuptake of NE and serotonin
    • M1 metabolite form - 6x potent in producing analgesia
  20. Ryzolt
    dosage form?
    Tablets (extended-release - 100, 200, 300 mg)
  21. Lasix
    generic?
    furosemide
  22. Lasix
    class?
    diuretic
  23. Lasix
    MOA?
    loop diuretic inhibits reabsorption of sodium and chloride
  24. Lasix
    dosage form?
    • Tablets (20, 40, 80 mg)
    • Oral Solution (10 mg/mL, 40 mg/5mL)
    • Injection (10 mg/mL)
  25. Bactrim
    generic?
    sulfamethoxazole with trimethoprim
  26. Bactrim
    class?
    antibiotic
  27. Bactrim
    MOA?
    • Trimethoprim inhibits exzyme dihydrofolate reductase
    • Sulfamethoxazole is competitive antagonist of para-aminobenzoic acid (PABA)
  28. Bactrim
    dosage form?
    • Tablets (regular, double)
    • Suspension
    • Injection
  29. Septra
    generic?
    sulfamethoxazole with trimethoprim
  30. Septra
    class?
    antibiotic
  31. Septra
    MOA?
    • Trimethoprim inhibits enzyme dihydrofolate reductase
    • Sulfamethoxazole is competitive antagonist of para-aminobenzoic acid (PABA)
  32. Septra
    dosage form?
    • Tablets (regular, double)
    • Suspension
    • Injection
  33. Nexium
    generic?
    esomeprazole magnesium
  34. Nexium
    class?
    gastric antisecretory
  35. Nexium
    MOA?
    esomeprazole is a proton pump inhibitor (PPI) that suppresses H+/K+ ATPase enzyme system at secretory surface of gastric parietal cell - inhibit final step of acid production
  36. Nexium
    dosage form?
    • Capsules (delayed - 20, 40 mg)
    • Granules for oral suspension (10, 20, 40 mg)
    • Powder for Injection (20, 40 mg)
  37. Singulair
    generic?
    montelukast sodium
  38. Singulair
    class?
    antiasthmatic
  39. Singulair
    MOA?
    Montelukast binds to CystLT1 receptors to block leukotrienes (correlated with asthma)
  40. Singulair
    dosage form?
    • Tablets (chewable, regular)
    • Granules
  41. Augmentin
    generic?
    amoxicillin with clavulanate potassium
  42. Augmentin
    class?
    antibiotic
  43. Augmentin
    MOA?
    • Amoxicillin is a bacteriocidal antibiotic that inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme
    • Clavulanic acid binds competitively to active sites of beta-lactamase enzymes to protect penicillin and cephalosporins from destruction (beta-lactamase bacteria cause otitis media)
  44. Augmentin
    dosage form?
    • Tablets (regular, chewable)
    • Oral Suspension
  45. Augmentin XR
    generic?
    amoxicillin with clavulanate potassium
  46. Augmentin XR
    class?
    antibiotic
  47. Augmentin XR
    MOA?
    • Amoxicillin is a bacteriocidal antibiotic that inhibits bacterial cell wall synthesis via acylation of transpeptidase enzyme
    • Clavulanic acid binds competitively to active sites of beta-lactamase enzymes to protect penicillin and cephalosporins from destruction (beta-lactamase bacteria cause otitis media)
  48. Augmentin XR
    dosage form?
    Tablets (extended)
  49. Amrix
    generic?
    cyclobenzaprine hydrochloride
  50. Amrix
    class?
    muscle relaxant
  51. Amrix
    MOA?
    does not act directly on skeletal muscle or at neuromuscular synapses, probably affect brain stem in CNS to cause overall reduction of tonic somatic motor activity influencing both alpha and gamma motoneurons
  52. Amrix
    dosage form?
    Capsules (extended)
  53. Flexeril
    generic?
    cyclobenzaprine hydrochloride
  54. Flexeril
    class?
    muscle relaxant
  55. Flexeril
    MOA?
    does not act directly on skeletal muscle or at neuromuscular synapses, probably affect brain stem in CNS to cause overall reduction of tonic somatic motor activity influencing both alpha and gamma motoneurons
  56. Flexeril
    dosage form?
    Tablets (5, 10 mg)
  57. Fexmid
    generic?
    cyclobenzaprine hydrochloride
  58. Fexmid
    class?
    muscle relaxant
  59. Fexmid
    MOA?
    does not act directly on skeletal muscle or at neuromuscular synapses, probably affect brain stem in CNS to cause overall reduction of tonic somatic motor activity influencing both alpha and gamma motoneurons
  60. Fexmid
    dosage form?
    Tablets (7.5 mg)
  61. Neurontin
    generic?
    gabapentin
  62. Neurontin
    class?
    anticonvulsant/antineuralgic
  63. Neurontin
    MOA?
    unknown, looks like GABA, but doesn't interact with that pathway
  64. Neurontin
    dosage form?
    • Tablets (600, 800 mg)
    • Capsules (100, 300, 400 mg)
    • Oral solution (250 mg/5 mL)
  65. Ativan
    generic?
    lorazepam
  66. Ativan
    class?
    antianxiety agent
  67. Ativan
    MOA?
    benzodiazepines facilitate the inhibitory neurotransmitter action of GABA, which mediates both pre- and post-synaptic inhibition in all regions of the CNS.
  68. Ativan
    dosage form?
    • Tablets (0.5 mg, 1 mg, 2 mg)
    • Injection (2 mg/mL, 4 mg/mL)
    • Solution, Intensol (2 mg/mL)
  69. Advair
    generic?
    fluticasone propionate with salmeterol xinafoate
  70. Advair
    class?
    antiasthmatic
  71. Advair
    MOA?
    • fluticasone propionate forms steroid-receptor complex in cytoplasm and enter nucleus to amek enzymes that carry out its antiallergy and anti-inflammatory actions
    • Salmeterol stimulates adenyl cyclase, increased cAMP associated with relaxation and inhibit release of mediators of immediate hypersensitivity from cells (mast cells)
  72. Advair
    dosage form?
    • Advair Diskus
    • Advair HFA
  73. Toprol-XL
    generic?
    metoprolol succinate
  74. Toprol-XL
    class?
    antihypertensive
  75. Toprol-XL
    MOA?
    cardioselective beta-1 adrenergic receptor blocker that decrease and inhibit stuff
  76. Toprol-XL
    dosage form?
    Tablets (extended)
  77. Mobic
    generic?
    meloxicam
  78. Mobic
    class?
    nonsteroidal anti-inflammatory (NSAID)
  79. Mobic
    MOA?
    inhibit cyclooxygenase to decrease synthesis of prostaglandins
  80. Mobic
    dosage form?
    • Tablets (7.5, 15 mg)
    • Oral suspension (7.5 mg/ 5 mL)
  81. Klor-Con
    generic?
    potassium chloride (oral)
  82. Klor-Con
    class?
    electrolyte
  83. Klor-Con
    MOA?
    potassium is the principal intracellular cation of most body tissues, replenish
  84. Klor-Con
    dosage form?
    • Tablets (controlled, coated, effervescent)
    • Capsules
    • Powder packets
    • Solution
  85. K-Dur
    generic?
    potassium chloride (oral)
  86. K-Dur
    class?
    electrolyte
  87. K-Dur
    MOA?
    potassium is the principal intracellular cation of most body tissues, replenish
  88. K-Dur
    dosage form?
    • Tablets (controlled, coated, effervescent)
    • Capsules
    • Powder packets
    • Solution
  89. Micro-K
    generic?
    potassium chloride (oral)
  90. Micro-K
    class?
    electrolyte
  91. Micro-K
    MOA?
    potassium is the principal intracellular cation of most body tissues, replenish
  92. Micro-K
    dosage form?
    • Tablets (controlled, coated, effervescent)
    • Capsules
    • Powder packets
    • Solution
  93. Coumadin
    generic?
    warfarin sodium (crystalline)
  94. Coumadin
    class?
    anticoagulant
  95. Coumadin
    MOA?
    antagonizes vitamin K to decrease vitamin K-dependent clotting factors
  96. Coumadin
    dosage form?
    • Tablets
    • Powder for Injection (lyophilized)
  97. Jantoven
    generic?
    warfarin sodium (crystalline)
  98. Jantoven
    class?
    anticoagulant
  99. Jantoven
    MOA?
    antagonizes vitamin K to decrease vitamin K-dependent clotting factors
  100. Jantoven
    dosage form?
    • Tablets
    • Powder for Injection (lyophilized)
  101. Diflucan
    generic?
    fluconazole
  102. Diflucan
    class?
    antifungal
  103. Diflucan
    MOA?
    highly selective inhibitor of fungal cytochrome P-450 sterol C-14 alpha-demethylation (less in mammalian cell), the accumulation is fungistatic
  104. Diflucan
    dosage form?
    • Tablets (50, 100, 150, 200 mg)
    • Powder for oral suspension (10 mg/mL, 40 mg/mL)
    • Injection (2 mg/mL)
  105. Seroquel
    generic?
    quetiapine fumerate
  106. Seroquel
    class?
    antipsychotic
  107. Seroquel
    MOA?
    multiple neurotransmitter antagonist especially at dopamine D2 and serotonin 5HT2 receptors
  108. Seroquel
    dosage form?
    Tablets (regular, extended - XR)
  109. Naprosyn
    generic?
    naproxen
  110. Naprosyn
    class?
    nonsteroidal anti-inflammatory (NSAID)
  111. Naprosyn
    MOA?
    inhibition of cyclooxygenase resulting in decreased prostaglandins
  112. Naprosyn
    dosage form?
    • Tablets (250 mg, 375 mg, 500 mg)
    • Suspension (125 mg/5 mL)
  113. EC-Naprosyn
    generic?
    naproxen
  114. EC-Naprosyn
    class?
    nonsteroidal anti-inflammatory (NSAID)
  115. EC-Naprosyn
    MOA?
    inhibition of cyclooxygenase resulting in decreased prostaglandins
  116. EC-Naprosyn
    dosage form?
    Tablets (delayed-release enteric coated)
  117. Topamax
    generic?
    topiramate
  118. Topamax
    class?
    antiepileptic
  119. Topamax
    MOA?
    unknown, maybe of 3 known properties - blcoekd sustained depolarization (state-dependent sodium channel blocking action), increase frequency of GABA-A receptor activation, let chlroide ions into neurons, antagonize kainate to activate kainate/AMPA receptor
  120. Topamax
    dosage form?
    • Tablets (25, 50, 100, 200 mg)
    • Sprinkle capsules (15, 25 mg)

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