Anti-Microbials

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Author:
ramy
ID:
106095
Filename:
Anti-Microbials
Updated:
2011-10-13 11:03:39
Tags:
anti microbials
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Description:
Anti-microbials
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  1. Pencillin
    • B-lactam
    • inhibit bacterial cell wall
  2. cephalosporin
    • B-lactam
    • inhibit bacterial cell wall
  3. carbapenems
    • B-lactam
    • inhibit bacterial cell wall
  4. Vancomycin
    • NON-B-lactam
    • inhibit bacterial cell wall
  5. Bacitracin
    • Non-B-lactam
    • inhibit bacterial cell wall
  6. Daptomycin
    Cell lysis via formation of membrane pores
  7. Oxazolidinones: Linozolid
    Inhibitor of protein synthesis via inhibiting microbial ribosomes
  8. Tetracyclines
    A: Inhibitor of protein synthesis via inhibiting initiation step by binding to the 30S ribosomal subunit, blocking the amino-acyl-tRNA. Blocks elongation too

    U: G- bacteria by entering the periplasmic space and then pumped into cytoplasm. G+ by using energy

    Minocycline & doscycycline pass directly through the lipid bilayer of both host and bacterial membranes

    Bacteriostatic
  9. Aminoglycosides
    Inhibitor of protein synthesis via inhibiting microbial ribosomes
  10. Chloramohenicol
    Inhibitor of protein synthesis via inhibiting microbial ribosomes
  11. Streptogramins
    Inhibitor of protein synthesis via inhibiting microbial ribosomes
  12. Macrolids
    Inhibitor of protein synthesis via inhibiting microbial ribosomes
  13. Lincosamides: Clindamycin
    Inhibitor of protein synthesis via inhibiting microbial ribosomes
  14. Rifamycins
    Inhibitor of RNA synthesis for mycobacteria
  15. Fluoroquinolones
    Inhibit topoisomerases
  16. Sulfa Drugs
    Inhibit folic acid synthesis
  17. Trimethoprim
    Inhibit folic acid synthesis

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