Prodrugs

Card Set Information

Author:
jaguavai
ID:
106184
Filename:
Prodrugs
Updated:
2011-10-03 21:19:24
Tags:
Pharm 410
Folders:

Description:
Prodrugs from Pharm 410
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  1. Heroin
    • Prodrug for morphine
    • Has acetyl groups instead of alcohols
    • Crosses BBB more readily, then hydrolyzed into morphine
  2. Nabumetone
    Prodrug designed to reduce toxicity
  3. Chloramphenicol
    Prodrug designed to be more water soluble
  4. Bambuterol
    • Prodrug for Terbutaline
    • Terbutaline experiences high first-pass metabolism
    • Prodrug administration results in prolonged plasma concentrations of the drug

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