APC 1

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Author:
azbenchaar
ID:
106567
Filename:
APC 1
Updated:
2011-10-06 11:40:21
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APC
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APC 1
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  1. Syringe sizes?
    0.3, 0.5, 1, 3, 5, 10, 20, 30, 50, 60 mL
  2. How accurate are TB syringes?
    to 0.05 mL
  3. Below what percent of the capacity of a syringe is a red flag to use a smaller syringe instead?
    20%
  4. When should catheter tip and oral syringes be used when compounding parenteral preperations?
    NEVER
  5. Needle lengths?
    0.25 to 3.5 inches
  6. Range of needle thickness?
    29 gauge (smallest) to 13 gauge (largest)
  7. Typical needle sizes seen in compounding?
    gauges 18 to 20

    lengths 1 to 1.5 inches
  8. What size filter do filter needles have?
    5 micron
  9. How long does USP <797> permit single dose vials to be stored continually in an ISO Class 5 environment?
    6 hours, unless labeled otherwise
  10. Gauge and length of ID needle?
    Gauge: 27

    Length: 3/8" to 5/8"
  11. Gauge and length of sc needle?
    Gauge: 24 to 29

    Length: 3/8" to 5/8"
  12. Volume for ID?
    0.1 mL
  13. Volume for sc?
    1 mL

    2 mL/hr
  14. Gauge and length of IM needle?
    Gauge: 20 to 22

    Length: 1" to 1.25"
  15. Volume for IM?
    Size dependent of site of administration (e.g., muscle size)

    <3 mL/site
  16. Gauge of needle for IV?
    Gauge: 19 to 25

    (dependent on size of patient and where we are administering)
  17. Volume for IV?
    Limited by site and catheter size

    (usually can infuse large volumes in a very short amount of time)
  18. All non-sterile water-containing preparations must be sterilized before what length of time?
    6 hrs
  19. HEPA filters remove what size particles?
    0.3 microns or larger
  20. Types of compounding, low risk?
    • Single transfers of
    • sterile dosage forms.

    • No more than 3
    • manufactured products
    • in an admixture.
  21. Types of compounding, low risk 12 hrs BUD?
    Same as low risk
  22. Types of compounding, medium risk?
    Compounding TPN.

    • Filling medication
    • reservoirs.

    Multiple transfers.
  23. Types of compounding, high risk?
    • Compounding using
    • non-sterile
    • ingredients.

    • Sterile ingredients
    • compounded in less
    • than ISO Class 5.
  24. Environment, low risk?
    ISO Class 5 or better

    • Buffer: at least ISO
    • Class 7
  25. Environment, low risk 12 hrs BUD?
    • ISO Class 5 LAFW or
    • CAI/CACI that requires
    • placement in Class 7,
    • but is not in Class 7

    No Buffer
  26. Environment, medium risk?
    ISO class 5 or better

    • Buffer: at least ISO
    • Class 7
  27. Environment, high risk?
    ISO class 5 or better

    • Buffer: at least ISO
    • Class 7
  28. BUD @ RT, low risk?
    48 hrs
  29. BUD @ RT, low risk 12 hrs BUD?
    12 hrs
  30. BUD @ RT, medium risk?
    30 hrs
  31. BUD @ RT, high risk?
    24 hrs
  32. BUD refrigerated, low risk?
    14 days
  33. BUD refrigerated, low risk 12 hrs BUD?
    12 hrs
  34. BUD refrigerated, medium risk?
    9 days
  35. BUD refrigerated, high risk?
    3 days
  36. BUD frozen, low risk?
    45 days
  37. BUD frozen, low risk 12 hrs BUD?
    12 hrs
  38. BUD frozen, medium risk?
    45 days
  39. BUD frozen, high risk?
    45 days
  40. How frequently should the PEC be cleaned and disinfected?
    • At start of shift, before each
    • batch, and at least every
    • 30minutes during continued use,
    • as well as after spills and
    • anytime surface contamination is
    • suspected

    (cleaning only needs to be done at start of shift, but disinfect for each)
  41. How frequently should buffer area counters and surfaces be cleaned and disinfected?
    Daily

    • (Easily accessible
    • surfaces in buffer area
    • are cleaned and
    • disinfected)
  42. How frequently should buffer area floors be cleaned and disinfected?
    Daily

    • (When no
    • compounding activity)
  43. How frequently should buffer area supply shelves be cleaned and disinfected?
    Weekly

    • (All items removed
    • from shelving,
    • counters, etc. for
    • cleaning)
  44. How frequently should walls, ceiling,
    shelving be cleaned and disinfected?
    Monthly
  45. How frequently should anterooms be cleaned and disinfected?
    Daily

    (After buffer area is mopped)
  46. How frequently should anteroom surfaces be cleaned and disinfected?
    Weekly
  47. How frequently should anteroom storage shelving, trash bins, chairs, storage bins be cleaned and disinfected?
    Monthly

    (All items removed from storage shelving)
  48. Air sampling frequency?
    Every 6 months minimum
  49. Sufficient volume of air being sampled?
    400 to 1000 liters
  50. Pressure between ISO Class 7 and rest of pharmacy?
    > or = 5 Pa
  51. Velocity between buffer and ante areas?
    > or = 0.2 meters per second
  52. mOsm/L for D5W?
    252 mOsm/L
  53. mOsm/L for NS?
    308 mOsm/L
  54. mOsm/L for LR?
    273 mOsm/L
  55. Isotonic range?
    250 to 375 mOsm/L
  56. Hypotonic range?
    <250 mOsm/L
  57. Hypertonic range?
    >375 mOsm/L

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