Pharmco

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Author:
sweetlu
ID:
106623
Filename:
Pharmco
Updated:
2011-10-29 08:28:19
Tags:
pharmco
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Description:
pharmco
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  1. 1st gen H1- receptor antagonists
    • dimenhydrinate
    • diphenhydramine
    • promethazine
  2. 2nd gen H1r antagonists
    • cetirizine
    • fexofenadine
    • loratidine
  3. triptans
    sumatriptan
  4. prostaglandins
    • (eicosanoids)
    • alprostadil
    • dinoprostone
    • latanoprost
  5. eicosanoid inhibitors
    • NSAIDS
    • glucocorticoids
  6. TTX
    • -Na channel blocker
    • -neuronal and muscular
    • -reduction of magnitude to prevention of AP
  7. Saxitoxin
    • -Na channel blocker
    • -neuronal and muscular
    • -reduction of magnitude to prevention of AP
  8. omega- Conotoxin
    • -Ca channel blocker
    • - blocks uptake of Ca at synaptic cleft, thus preventing release of neurotransmitter vesicles
  9. mu-Conotoxin
    • -Na channel blocker
    • -muscle
    • - reduction of magnitude to prevention of AP
  10. Dendrotoxin
    • -K channel blocker
    • -neuronal
  11. Tetanus toxoid
    • - ACh release inhibitor
    • - IPSP inhibition
  12. Botulinum toxin
    • -ACh release inhibitor
    • -prevention of AP at NMJ

  13. Phyiostigmine
    • -AChE inhibitor
    • -preventing breakdown of ACh in the NMJ
  14. DFP
    • -AChE inhibitor
    • -preventing breakdown of ACh in the NMJ
  15. delta- Tubocuraine
    -AChR channel blocker
  16. alpha- Bungarotoxin
    -AChR channel blocker
  17. pharmacokinetics
    • what the body does to the drug
    • -route of administration
    • -absorption
    • -distribution
    • -elimination
    • -metabolism
  18. pharmacodynamics
    • what the drug does to the body
    • -mechanism of action
  19. pharmacological action
    -functional or physiological modification
  20. pharmacological effect
    observable effect (see, hear etc)

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