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What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the aldosterone antagonist spironolactone (Aldactone)?
- Child
- Liver failure or disease
- Concurrent use of prescribed drugs that raise potassium levels
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What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the calcium channel blockers (dihydropyridines) nifedipine (Adalat, Procardia)?
- Heart failure
- Gastroesophageal reflex disease
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the loop diuretic furosemide (Lasix)?
- Renal or liver disorders
- Acute myocardial infarction (MI) with cardiogenic shock
- Ventricular dysrhythmias
- Heart failure
- Diarrhea
- History of gout or systemic lupus erythematosus
- Diabetes mellitus
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What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the cardiac glycosides digoxin (Lanoxin)?
- Hypokalemia
- Impaired renal function
- An infant, child or older adult
- Acute myocardial infarction (MI) and severe heart failure
- Dysrhythmias, such as incomplete heart block
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the angiotensin-converting enzyme (ACE) inhibitor drug captopril (Capoten)?
- Decreased renal function
- Bone marrow depression or use of other drugs that cause immunosuppression
- Autoimmune disorders, such as rheumatoid arthritis
- Cardiovascular disease
- Cerebrovascular disease
- Heart failure
- Hyperkalemia
- Hyponatremia
- Older adult
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the class IA/sodium channel blocker drugs quinidine (Apo-Quinidine, Novo-Quinidine) and procainamide (Pronestyl)?
- Impaired liver or kidney function
- First degree heart block
- Electrolyte imbalance
- Asthma
- Procainamide: Heart failure (HF), myocardial infarction (MI), digitalis-caused dysrhythmia, aspirin allergy
- Quinidine: Myasthenia gravis
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What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the direct-acting vasodilator (hydralazine) drug hydralazine (Apresoline)?
- Coronary heart disease
- Stroke
- Renal dysfunction
- Systemic lupus erythematosus (SLE)
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the class III/potassium channel blocker amiodarone (Cordarone)?
- Any hepatic disease
- Any thyroid dysfunction
- Heart failure
- Electrolyte imbalance or hypovolemia
- Pulmonary disease, such as COPD
- Heart surgery
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the alpha/beta blocker carvedilol (Coreg)?
- Child or adolescent younger than 18 years old
- Diabetes mellitus
- Renal or liver disorders
- Peripheral vascular disease
- Depressive disorders
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the class IC/sodium channel blockers flecainide (Tambocor) and propafenone (Rythmol)?
- Allergy to lidocaine and other amide anesthetics
- Atrial fibrillation
- Cardiac, renal or hepatic disease
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the class IB/sodium channel blocker, lidocaine (Xylocaine)?
- Renal or liver disorders
- Heart failure
- Respiratory depression or low blood oxygen levels
- Fluid volume deficits
- Myasthenia gravis
- Family history of malignant hyperthermia
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the nitrate drugs nitroglycerin (Nitrostat, Nitro-Dur, Nitro-Bid) and isosorbide dinitrate (Isordil)?
- Hypotension
- Hypovolemia
- Hyperthyroidism
- Liver disease
- Conditions that cause dry mouth (sublingual and transmucosal forms)
- Early myocardial infarction (MI)
- Older adult
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the class II/beta adrenergic blocker propranolol (Inderal)?
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the class II/beta adrenergic blocker propranolol (Inderal)?
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the alpha1 adrenergic blocker doxazosin (Cardura)?
Renal or hepatic disease
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the class IV/calcium channel blocker verapamil (Calan)?
- Liver or kidney disfunction
- Duchennes muscular dystrophy
- Myocardial infarction (MI)
- Gastrointestinal obstruction or ileus, gastroesophageal reflux disease, hiatal hernia
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the HMG-CoA reductase inhibitor (statin) drug simvastatin (Zocor)?
- Family history of high cholesterol (homozygous familial hypercholesterolemia)
- History of liver disorders
- Diabetes mellitus
- Alcoholism
- Renal disorders
- Seizure disorders
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the fibrate drug gemfibrozil (Lopid)?
- Hypothyroidism
- Diabetes mellitus
- Any renal impairment
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the adrenergic neuron blocker reserpine (Serpalan, Sk-Reserpine)?
- Cardiac dysrhythmias or cerebrovascular disease
- History of peptic ulcer
- Chronic respiratory disease
- Older adult
- Epilepsy
- Gallstones
- Parkinson's disease
- Pheochromocytoma (adrenal gland tumor)
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the centrally acting alpha2 agonist clonidine (Catapres)?
- Recent myocardial infarction (MI), severe cardiac disease or cerebrovascular disease
- Diabetes mellitus
- Renal or liver disorders
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the angiotensin receptor blocker (ARB) losartan (Cozaar)?
- Concurrent diuretic use
- Hyperkalemia
- Liver or renal disorders
- First trimester of pregnancy
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the phosphodiesterase inhibitor milrinone (Primacor)?
- Renal impairment
- Atrial flutter or fibrillation
- Older adult
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the potassium-sparing diuretic spironolactone (Aldactone)?
- Greatly increased BUN (blood urea nitrogen) levels
- Mild or moderate renal insufficiency
- Liver disease
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the sympathomimetic drug dobutamine (Dobutrex)?
- Use with MAOI or tricyclic antidepressants or with general anesthetics
- Heart disease, hypertension or tachycardia
- Hyperthyroidism
- Angina pectoris
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the thiazide diuretic hydrochlorothiazide (HydroDIURIL)?
- Heart failure
- Cirrhosis of the liver
- Renal disorders
- History of gout or systemic lupus erythematosus
- Diabetes mellitus
- Older adult
- Asthma
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the direct renin inhibitor aliskiren (Tekturna)?
- Older adult
- Patient taking any drug that increases potassium levels, such as ACE inhibitors
- Patient with low creatinine clearance
- Diabetes mellitus
- History of angioedema
- Respiratory disorders or history of airway surgery
-
What factors increase the risk of side or adverse effects and thus warrant precautions for a patient taking the beta adrenergic blockers atenolol (Tenormin) and metoprolol (Lopressor)?
- A patient with heart failure controlled by digitalis and diuretics
- Asthma, COPD or other chronic respiratory disorder
- Renal or liver disorders
- Myasthenia gravis
- Hyperthyroidism
- Diabetes mellitus
- Major depression
- Pheochromocytoma (adrenal gland tumor)
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