What important instructions should the health care professional give the patient who is taking the sulfonamide drug trimethoprim and sulfamethoxazole (Bactrim, Septra)?
- Report gastrointestinal (GI) symptoms.
- Take with food to minimize GI symptoms.
- Report rash and hives.
- Report fatigue, pallor, easy bruising, or new infections.
- Report watery or bloody diarrhea.
- Report pain in mouth, difficulty eating, or vaginal burning or discharge.
- Report onset of rash and/or blisters on the skin.
- Be aware that sulfonamides decrease the effectiveness of oral contraceptives; use an alternate form of contraception.