Dose Form Exam II Definitions

Solid dosage form prepared by compression or molding of powder granulated drugs and with the aid of suitable pharmaceutical excipients

• Compressed
• Multiple compressed
• Sugar Coated
• Film Coated
• Gelatin coated
• Enteric Coated
• Buccal
• Sublingual
• Chewable
• Lozenges,troches, drops pastilles
• Lolli Pops
• Effervescent
• Molded
• Tablet Triturates
• Rapids dissolve
• Extended release

Single compression of all ingrediants

• For separation of incompatible drugs or for modified release
• Multiple layered tablet; multiple feed and pultiple compression of fill within a single die
• Tablet within a tablet; Core tablet is placed precisely within the die for compression with surrounding fill

• Several layers of colored or uncolored sugar solution, sucrose, gelatin, acacia, PVP (Polyvinylpyrrolidone)
• Final tablet of up to 50% of size and weight of uncoated tabletq

product specific identification codes and distinctive stmbols

Cloth or canvas impregnated with carnuba wax/bees wax dissolved in acetone

• Thin layer of aqueous or non-aqueous polymer solution (plastic-like material), cellulose acetate phthalate, cellulose ether polymers
• Protection, color, durability, less bulkiness, less time consuming

Capsule-shaped compressed tablet coated with gelatin

• Protection of drug, patient gastric mucosa, or enhanced absorption
• Based on transit time required for the passage of the dosage form from the stomach into the intestines, or based upon th pH of environment
• Delayed release features
• Materials, shellac phthalate derivatives

Placed in the cheek pouch, dissolve slowly absorption through the oral mucosa

Placed under the tongue, prompt dissolution, absorption throughout the orl mucosa

• Chewed and dissolve in the mouth, made with creamy base (mannitol, sorbitol, xylitol=sugar free)
• Negative heat of solution leaves cool mouth feeling upon dissolution, flavored and colored, children and adults who have difficulty swallowing.

• Hard candy like (sugar or sugar free) or gummy like (gelatin-based)
• Dissoved or distintgrate slowly
• Heat stableingrediants
• Local effects

• Sugar based lozenges on a stick
• Fentanyl

• Compression of effervescent salts taht liberate carbon dioxide when dissolved in water
• Should not be swallowed whole

Molding and soft compaction, hand operated tablet press

"Old Fashioned" tablets containing small amounts of potent drugs and prepared with minimal compression to allow ease of crushing for compounding or rapid dissolution

• SUPER DISINTEGRANTS
• Dissolution within 15to30 seconds
• Very water soluable excipients that attract water into the tablet

Drug loading, taste masking, and friability