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Tablet
Solid dosage form prepared by compression or molding of powder granulated drugs and with the aid of suitable pharmaceutical excipients
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Tablet types
- Compressed
- Multiple compressed
- Sugar Coated
- Film Coated
- Gelatin coated
- Enteric Coated
- Buccal
- Sublingual
- Chewable
- Lozenges,troches, drops pastilles
- Lolli Pops
- Effervescent
- Molded
- Tablet Triturates
- Rapids dissolve
- Extended release
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Compressed tablet
Single compression of all ingrediants
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Multiple Compressed Tablets
- For separation of incompatible drugs or for modified release
- Multiple layered tablet; multiple feed and pultiple compression of fill within a single die
- Tablet within a tablet; Core tablet is placed precisely within the die for compression with surrounding fill
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Sugar Coated Tablets
- Several layers of colored or uncolored sugar solution, sucrose, gelatin, acacia, PVP (Polyvinylpyrrolidone)
- Final tablet of up to 50% of size and weight of uncoated tabletq
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Imprinting
product specific identification codes and distinctive stmbols
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Polishing
Cloth or canvas impregnated with carnuba wax/bees wax dissolved in acetone
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Film Coated Tablet
- Thin layer of aqueous or non-aqueous polymer solution (plastic-like material), cellulose acetate phthalate, cellulose ether polymers
- Protection, color, durability, less bulkiness, less time consuming
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Gelatin Coated Tablets
Capsule-shaped compressed tablet coated with gelatin
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Enteric Coated Tablets
- Protection of drug, patient gastric mucosa, or enhanced absorption
- Based on transit time required for the passage of the dosage form from the stomach into the intestines, or based upon th pH of environment
- Delayed release features
- Materials, shellac phthalate derivatives
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Buccal Tablets
Placed in the cheek pouch, dissolve slowly absorption through the oral mucosa
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Sublingual Tablets
Placed under the tongue, prompt dissolution, absorption throughout the orl mucosa
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Chewable Tablets
- Chewed and dissolve in the mouth, made with creamy base (mannitol, sorbitol, xylitol=sugar free)
- Negative heat of solution leaves cool mouth feeling upon dissolution, flavored and colored, children and adults who have difficulty swallowing.
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Lozenges, troches, Drop Pstilles
- Hard candy like (sugar or sugar free) or gummy like (gelatin-based)
- Dissoved or distintgrate slowly
- Heat stableingrediants
- Local effects
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Lollipops
- Sugar based lozenges on a stick
- Fentanyl
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Effervescent Tablet
- Compression of effervescent salts taht liberate carbon dioxide when dissolved in water
- Should not be swallowed whole
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Molded Tablets
Molding and soft compaction, hand operated tablet press
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Tablet Triturates
"Old Fashioned" tablets containing small amounts of potent drugs and prepared with minimal compression to allow ease of crushing for compounding or rapid dissolution
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Rapid Dissolving Tablets
- SUPER DISINTEGRANTS
- Dissolution within 15to30 seconds
- Very water soluable excipients that attract water into the tablet
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What are some inherent problems with rapid dissolving tablet?
Drug loading, taste masking, and friability
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