Dose Form Exam II Definitions

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Anonymous
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107195
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Dose Form Exam II Definitions
Updated:
2011-10-08 00:34:28
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Dose Form Tablets Oinemnts Suppositories Solutions
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Dose form exam II definitions
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  1. Tablet
    Solid dosage form prepared by compression or molding of powder granulated drugs and with the aid of suitable pharmaceutical excipients
  2. Tablet types
    • Compressed
    • Multiple compressed
    • Sugar Coated
    • Film Coated
    • Gelatin coated
    • Enteric Coated
    • Buccal
    • Sublingual
    • Chewable
    • Lozenges,troches, drops pastilles
    • Lolli Pops
    • Effervescent
    • Molded
    • Tablet Triturates
    • Rapids dissolve
    • Extended release
  3. Compressed tablet
    Single compression of all ingrediants
  4. Multiple Compressed Tablets
    • For separation of incompatible drugs or for modified release
    • Multiple layered tablet; multiple feed and pultiple compression of fill within a single die
    • Tablet within a tablet; Core tablet is placed precisely within the die for compression with surrounding fill
  5. Sugar Coated Tablets
    • Several layers of colored or uncolored sugar solution, sucrose, gelatin, acacia, PVP (Polyvinylpyrrolidone)
    • Final tablet of up to 50% of size and weight of uncoated tabletq
  6. Imprinting
    product specific identification codes and distinctive stmbols
  7. Polishing
    Cloth or canvas impregnated with carnuba wax/bees wax dissolved in acetone
  8. Film Coated Tablet
    • Thin layer of aqueous or non-aqueous polymer solution (plastic-like material), cellulose acetate phthalate, cellulose ether polymers
    • Protection, color, durability, less bulkiness, less time consuming
  9. Gelatin Coated Tablets
    Capsule-shaped compressed tablet coated with gelatin
  10. Enteric Coated Tablets
    • Protection of drug, patient gastric mucosa, or enhanced absorption
    • Based on transit time required for the passage of the dosage form from the stomach into the intestines, or based upon th pH of environment
    • Delayed release features
    • Materials, shellac phthalate derivatives
  11. Buccal Tablets
    Placed in the cheek pouch, dissolve slowly absorption through the oral mucosa
  12. Sublingual Tablets
    Placed under the tongue, prompt dissolution, absorption throughout the orl mucosa
  13. Chewable Tablets
    • Chewed and dissolve in the mouth, made with creamy base (mannitol, sorbitol, xylitol=sugar free)
    • Negative heat of solution leaves cool mouth feeling upon dissolution, flavored and colored, children and adults who have difficulty swallowing.
  14. Lozenges, troches, Drop Pstilles
    • Hard candy like (sugar or sugar free) or gummy like (gelatin-based)
    • Dissoved or distintgrate slowly
    • Heat stableingrediants
    • Local effects
  15. Lollipops
    • Sugar based lozenges on a stick
    • Fentanyl
  16. Effervescent Tablet
    • Compression of effervescent salts taht liberate carbon dioxide when dissolved in water
    • Should not be swallowed whole
  17. Molded Tablets
    Molding and soft compaction, hand operated tablet press
  18. Tablet Triturates
    "Old Fashioned" tablets containing small amounts of potent drugs and prepared with minimal compression to allow ease of crushing for compounding or rapid dissolution
  19. Rapid Dissolving Tablets
    • SUPER DISINTEGRANTS
    • Dissolution within 15to30 seconds
    • Very water soluable excipients that attract water into the tablet
  20. What are some inherent problems with rapid dissolving tablet?
    Drug loading, taste masking, and friability

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