Drug name/class

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azbenchaar
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107205
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Drug name/class
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2011-12-10 19:58:54
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Drug name/class
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  1. acetylcholine (Miochol-E)
    Direct Acting Muscarinic Agonist
  2. carbachol (Isopto Carbachol)
    Direct Acting Muscarinic Agonist
  3. methacholine (Provocholine)
    Direct Acting Muscarinic Agonist
  4. bethanechol (Urecholine)
    Direct Acting Muscarinic Agonist
  5. pilocarpine (Salagen/Ocusert Pilo)
    Direct Acting Muscarinic Agonist
  6. edrophonium (Tensilon)
    reversible cholinesterase inhibitor
  7. physostigmine/eserine
    reversible cholinesterase inhibitor
  8. neostigmine (Prostigmin)
    reversible cholinesterase inhibitor
  9. pyridostigmine (Mestinon)
    reversible cholinesterase inhibitor
  10. rivastigmine (Exelon)
    reversible cholinesterase inhibitor
  11. donepezil (Aricept)
    reversible cholinesterase inhibitor
  12. carbamate insecticides (e.g. Carbaryl)
    reversible cholinesterase inhibitor
  13. DFP/diisopropylfurophosphate/isoflurophate and echothisophate
    irreversible cholinesterase inhibitor
  14. organophosphate insecticides (e.g. Parathion, Malathion)
    irreversible cholinesterase inhibitor
  15. nerve gases used in chemical warfare (e.g. Sarin)
    irreversible cholinesterase inhibitor
  16. sildenafil (Viagra)
    • cGMP phosphodiesterase
    • (PDE-5) inhibitor
  17. vardenafil (Levitra)
    • cGMP phosphodiesterase
    • (PDE-5) inhibitor
  18. tadalafil (Cialis)
    • cGMP phosphodiesterase
    • (PDE-5) inhibitor
  19. pralidoxime/2-PAM (Protopam)
    cholinesterase reactivator
  20. botulinum toxin (BOTOX)
    toxin

    (proteolytically degrades the SNAP-25 protein, a type of SNARE protein that is required for vesicle fusion and therefore release of ACh from presynaptic cholinergic neurons into the synaptic cleft)
  21. atropine, hyoscyamine, and homatropine
    Muscarinic Antagonist (Anticholinergic)
  22. scopolamine and methscopolamine
    Muscarinic Antagonist (Anticholinergic)
  23. dicyclomine (Bentyl)
    Muscarinic Antagonist (Anticholinergic)
  24. propantheline
    Muscarinic Antagonist (Anticholinergic)
  25. glycopyrrolate (Robinul)
    Muscarinic Antagonist (Anticholinergic)
  26. ipratropium (Atrovent)
    Muscarinic Antagonist (Anticholinergic)
  27. tiatropium (Spiriva)
    Muscarinic Antagonist (Anticholinergic)
  28. benztropine (Cogentin)
    Muscarinic Antagonist (Anticholinergic)
  29. trihexyphenidyl (Artane)
    Muscarinic Antagonist (Anticholinergic)
  30. tolterodine (Detrol)
    Muscarinic Antagonist (Anticholinergic)
  31. oxybutynin (Ditropan)
    Muscarinic Antagonist (Anticholinergic)
  32. solifenacin (VESIcare)
    Muscarinic Antagonist (Anticholinergic)
  33. tropicamide (Mydriacyl)
    Muscarinic Antagonist (Anticholinergic)
  34. epinephrine (Adrenalin, EpiPen, Primatene Mist); E
    Mixed or nonselective agonist

    (𝝰1 ≈ 𝝰2 ≈ β1≈ β2)
  35. norepinephrine (Levophed); NE
    Mixed or nonselective agonist

    (𝝰1 ≈ 𝝰2 ≈ β1>>β2)
  36. isoproterenol (Isuprel)
    Mixed or nonselective agonist

    1≈ β2>> all others)
  37. dopamine (Intropin); DA
    Mixed or nonselective agonist

    (D receptors > β1 > 𝝰1 >> all others)
  38. dobutamine (Dobutrex)
    Selective β1-agonist
  39. albuterol (Proventil)
    Selective β2-agonist
  40. metaproterenol
    Selective β2-agonist
  41. pirbuterol (Maxair)
    Selective β2-agonist
  42. salmeterol (Serevent)
    Selective β2-agonist
  43. terbutaline
    Selective β2-agonist
  44. phenylephrine
    Selective 𝝰1-agonist
  45. midodrine (ProAmatine)
    Selective 𝝰1-agonist
  46. cocaine
    Indirect-acting sympathomimetic
  47. pseudoephedrine (Sudafed)

    ephedrine
    Indirect-acting sympathomimetic
  48. amphetamine

    methamphetamine
    Indirect-acting sympathomimetic
  49. methylphenidate (Ritalin)
    Indirect-acting sympathomimetic
  50. phenytoin (Dilantin)
    Traditional Antiepileptic

    Blocks voltage-gated Na+ channels on neuronal axons
  51. carbamazepine (Tegretol, Carbatrol)
    Traditional Antiepileptic

    Blocks voltage-gated Na+ channels on neuronal axons
  52. ethosuximide (Zarontin)
    Traditional Antiepileptic

    Blocks T-type Ca2+ channels located on the postsynaptic membrane
  53. valproic acid/valproate (Depakote, Depakene)
    Traditional Antiepileptic/Antiseizure drug (Treatment for migraines and other headaches)

    Blocks voltage-gated Na+ channels on neuronal axons

    Blocks T-type Ca2+ channels located on the postsynaptic membrane
  54. benzodiazepines, e.g.:

    clonazepam (Klonopin)
    clorazepate (Tranxene-SD)
    Traditional Antiepileptic

    Increase GABA effects at GABAA post-synaptic receptor
  55. fosphenytoin (Cerebyx)
    Traditional Antiepileptic
  56. gabapentin (Neurontin)
    Newer Antiepileptic/Antiseizure drug (Treatment for migraines and other headaches)
  57. oxcarbazepine (Trileptal)
    Newer Antiepileptic

    Blocks voltage-gated Na+ channels on neuronal axons
  58. lamotrigine (Lamictal)
    Newer Antiepileptic
  59. levetiracetam (Keppra)
    Newer Antiepileptic
  60. ergotamine tartrate (Ergomar)
    Ergot alkaloid (Treatment for migraines and other headaches)
  61. dihydroergotamine (D.H.E. 45)
    Ergot alkaloid (Treatment for migraines and other headaches)
  62. methysergide maleate (Sansert)
    Serotonin antagonist (Treatment for migraines and other headaches)
  63. sumatriptan (Imitrex)
    First generation specific 5-HT1B/1D agonist (Treatment for migraines and other headaches)
  64. zolmitriptan (Zomig, Zomig ZMT)
    Second generation specific 5-HT1B/1D agonist (Treatment for migraines and other headaches)
  65. metoclopramide (Reglan)
    Dopamine antagonist (Antiemetic)
  66. prochlorperazine (Compazine)
    Dopamine antagonist (Antiemetic)

    Relieves headache headache pain also
  67. midrin (Isometheptene 65 mg + dichloralphenazone 100 mg + acetaminophen 325 mg)
    Analgesic (Treatment for migraines and other headaches)
  68. amitriptyline (Elavil)
    Tri-cyclic antidepressant (Treatment for migraines and other headaches)
  69. topiramate (Topamax)
    Antiseizure drug (Treatment for migraines and other headaches)
  70. morphine
    Strong analgesic (µ agonist)
  71. codeine
    Strong analgesic (µ agonist)
  72. fentanyl
    Strong analgesic (µ agonist)
  73. heroin
    Strong analgesic (µ agonist)
  74. hydrocodone (Vicodin, Lortab, Norco, others)
    Strong analgesic (µ agonist)
  75. hydromorphone (Dilaudid)
    Strong analgesic (µ agonist)
  76. meperidine (Demerol)
    Strong analgesic (µ agonist)
  77. methadone (Dolophine)
    Strong analgesic (µ agonist)
  78. oxycodone (Percodan, Percocet, OxyContin)
    Strong analgesic (µ agonist)
  79. propoxyphene (Darvon, Darvocet)
    Strong analgesic (µ agonist)
  80. pentazocine (Talwin)
    Partial agonist and mixed agonist/antagonist analgesic
  81. buprenorphine (Buprenex, Sabutrex, Suboxone)
    Partial agonist and mixed agonist/antagonist analgesic
  82. butorphanol (Stadol)
    Partial agonist and mixed agonist/antagonist analgesic
  83. tramadol (Ultram)
    Partial agonist and mixed agonist/antagonist analgesic
  84. naloxone (Narcan)
    Opioid antagonist
  85. naltrexone (ReVia)
    Opioid antagonist
  86. methylnaltrexone (Relistor)
    Opioid antagonist
  87. acetazolamide (Diamox)
    Carbonic anhydrase inhibitor
  88. mannitol (Osmitrol)
    Osmotic diuretic
  89. furosemide (Lasix)
    • Loop diuretic/High-ceiling diuretic
    • (Inhibitors of apical Na+/K+/2Cl- symport)
  90. ethacrynic acid (Edecrin)
    • Loop diuretic/High-ceiling diuretic
    • (Inhibitors of apical Na+/K+/2Cl- symport)
  91. hydrochlorothiazide (Esidrix, Hydrodiuril)
    Thiazide diuretic (inhibitor of apical Na+/Cl- symport)
  92. chlorothiazide (Diuril)
    Thiazide diuretic (inhibitor of apical Na+/Cl- symport)
  93. chlorthalidone (Hygroton)
    Thiazide-like diuretic (inhibitor of apical Na+/Cl- symport)
  94. indapamide (Lozol)
    Thiazide-like diuretic (inhibitor of apical Na+/Cl- symport)
  95. triamterene (Dyrenium)
    K+ sparing diuretic (inhibitor of renal Na+ channels)
  96. amiloride (Midamor)
    K+ sparing diuretic (inhibitor of renal Na+ channels)
  97. spironolactone (Aldactone)
    K+ sparing diuretic (aldosterone antagonist)
  98. eplerenone (Inspra)
    K+ sparing diuretic (aldosterone antagonist)
  99. drospirenone + ethinyl estradiol (Yasmin)
    K+ sparing diuretic (aldosterone antagonist)
  100. desmopressin acetate (1-Deamino-8-D-Arginine Vasopressin) (DDAVP, Stimate)
    Anti-diuretic
  101. hydrochlorothiazide (Microzide)
    Thiazide diuretic (inhibitor of apical Na+/Cl- symport)
  102. chlorthalidone (Thalitone)
    Thiazide-like diuretic (inhibitor of apical Na+/Cl- symport)
  103. reserpine
    Adrenergic neuron blocker
  104. methyldopa
    Adrenergic neuron blocker
  105. clonidine (Catapres)
    Adrenergic neuron blocker

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