Mechanisms Eicosanoids

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Author:
anasolhowell
ID:
107325
Filename:
Mechanisms Eicosanoids
Updated:
2011-10-08 18:00:06
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Mechanisms Eiconsanoids
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Mechanisms Eiconsanoids
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  1. What are the actions of Prostaglandins (PGE2)?
    • Vasodilation
    • Potentiate edema
    • Induces fever
    • Causes pain
  2. What are the actions of Prostacyclins (PGI2)?
    • Vasodilation
    • Inhibits platelet aggregation
    • Balances with Thromboxanes
  3. Where is the primary site of synthesis of Prostaglandins (PGE2)?
    Widely distributed (except red blood cells-RBC)
  4. Where is the primary site of synthesis of Prostacyclins (PGI2)?
    Vascular endothelium
  5. What are the actions of Thromboxanes? (TxA2)?
    • Vasoconstriction
    • Promotes platelet aggregation
    • Balances action of Prostacylins
  6. What are the actions of Leukotrienes?
    • Vasoconstriction
    • Bronchoconstriction
    • Increased vascular permeability
    • Increased PMN (Polymorhphonuclear Neutrophils) chemotaxis

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