How does the chemotaxis signaling pathway adapt to the current attractant concentration?
CheR constantly adds methyl groups to specific sites on the MCPs -> increases the ability of the MCP to activate CheA at any [attractant]
CheB removes methyl groups from the MCPs -> reducing their ability to activate CheA at any [attractant]. CheB is a response regulator whose receiver domain is phosphorylated by CheA - increases the activity of CheB. CheB is activated at the same time as they CheY pathway