341 - Anticholinergic Drugs

Card Set Information

Author:
estee08
ID:
107914
Filename:
341 - Anticholinergic Drugs
Updated:
2011-10-10 21:35:03
Tags:
pharmacy
Folders:

Description:
PHAR 341 - Anticholinergic Drugs
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user estee08 on FreezingBlue Flashcards. What would you like to do?


  1. Atropine
    • Antimuscarinic Drug
    • Alkaloid of belladona plant
    • Competitive antagonist of all muscarinic receptors
    • Effects: Decreased parasympathetic tone effects, CNS drowsiness, CNS hallucinations, decreased sweating
    • Acute Myocardial Infarction/Cardiopulmonary Resuscitation: reverses sustained bradycardia, reduces ventricular arrythmias, treats nausea induced by morphine (morphine being used to treat for pain)
    • Pesticide Overdose: counteracts the effect of increased ACh at muscarinic receptors
    • Preoperative: counteracts general anesthetic-induced bradycardia, salivation, and increased bronchial secreations
    • Eye Exams: produces mydriasis (pupil dilation) and cycloplegia (inability to accommodate)
  2. Scopolamine
    • Antimuscarinic Drug
    • Alkaloid of belladona plant
    • Competitive antagonist of all muscarinic receptors
    • More fatigue and drowsiness than atropine (because it crosses blood-brain barrier easier), more mydriasis and cycloplegia (blurred vision) than atropine, less heart effects than atropine
    • Motion Sickness: decreases salivary secretions and GI motility, decreases nausea in CNS.
  3. Ipratropium and Tiotropium
    • Antimuscarinic Drug
    • Competitive antagonist of all muscarinic receptors
    • Inhaler (low systemic side effects)
    • Asthma: topical bronchodilator with a dry mouth side effect
  4. Benztropine
    • Antimuscarinic Drug
    • Competitive antagonist of all muscarinic receptors
    • Parkison's Disease: Parkinson's is caused by a decrease of dopamine in the brain. This drug decreases ACh which results in an increase of dopamine. Also reduces drooling with this disorder.
  5. Pirenzapine
    • M1 selective antagonist
    • Not available anymore
    • Peptic Ulcer Disease: Decreases gastric acid secretion. Lower incidence of dry mouth and tachycardia side effects.
  6. Oxybutnin
    • M1 and M3 selective antagonist
    • Urinary Incontinence (frequent urination/urge to urinate): decreases frequency of bladder muscle contractions, decreases desire to void. High incidence of dry mouth, drowsiness, constipation and blurred vision.
  7. Tolterodine
    • Not muscarinic selective
    • Urinary Incontinence: this drug is more selective for the bladder over the salivary gland. Lower incidence of dry mouth than oxybutnin but it's less effective for incontinence.
  8. Solifenacin
    • M3 receptor antagonist
    • Urinary Incontinence: Less dry mouth than oxybutnin.

What would you like to do?

Home > Flashcards > Print Preview