chronic inflammatory disease fo the joints, particularly the large weight-bearing joitns (knees, hips) and joints that move repeatedly (shoulders, neck hands). Usue begins in middle age, can begin earlier due to overuse or trauma. joint pain, stiffness, inflammation from constant wear and tear, worse if overweight. cartilage becomes roughened and then wears away in spots. bone ends rub.
treatment: analgesic drugs, nonsteroidal anti-inflammatory drugs; intra-articular injection of corticosteriod drug