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Identify the average range for adult blood volume?
What are the functions of the cardiovascular system (blood)?
- A. transports
- B. temp. maintenance
- C. fluid balance
- D. acid-base balance
- E. hemostasis
- F. resistance
fluid portion of unclotted whole blood
fluid portion of clotted whole blood
red blood cells
white blood cells
What is the function of erythrocytes?
transport O2 (hemoglobin)
What is the function of neutrophils?
phagotype > promotes inflamation
What is the function of eosinophils?
phagotype > anti-inflamatory
What is the function of basophils?
phagotype > inflamatory
What are the functions of momocytes/macrophages?
phagocytosis, immunity, inflamatory
What is the function of lymphocytes?
What is the function of thrombocytes?
Outline erythropoieses's regulation?
hypoxia > kidney > erythropoietin > red marrow > RBCs
What are the required dietary factors of erythrocytes?
- 1. nutritional- iron, amino acids, folic acids, B12
- 2. intrinsic factor- made by stomach B12- absorption (sm int.)
Where is intrinsic factor produced and what is it's function?
stomach, B12 absorption (sm int.)
What are the blood types of the ABO group?
A, B, AB, O
Which antigens and antibodies are associated with each type?
- A > A, anti B
- B > B, anti A
- AB > both antigens, no antibodies
- O > no antigens, both antibodies
What is unique about ABO group antibodies?
What is responsible for most transfusion reactions?
recipient's antibodies targeting donor's antigens
Identify the universal donor and recipient and explain why each qualifies?
- O-, no RBC antigens to be targeted
- AB+, no antibodies to target RBCs
How are people classified with regard to the Rh D antigen?
Outline the general setting in which antibodies against the Rh D antigen would produce?
antibodies can be formed by a Rh neg person if exposed to Rh D antigens on the RBCs of a Rh+ person
stoppage and bleeding
List the sequence of events involved in hemostasis?
- 1. vascular spasm
- 2. platelet plug
- 3. coagulation
cascading series of reactions d/t clotting factors > fibrin clot