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The flashcards below were created by user
embryo
on FreezingBlue Flashcards.
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Omeprazole
inhibits gastric H+ ATPase from transporting H into lumen of SI; ulcer Rx
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tetrodotoxin
block VG Na channels and prevent AP
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lidocaine
block VG Na channels and prevent AP
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TEA
blocks VG K channels, outward K current and repolarization
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Nifedipine
Ca channel blocker
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Verapamil
Ca channel blocker
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Botulinis toxin
blocks Ach release from pre-synaptic terminal; paralysis of skeletal m and death from respiratory failure (diaphragm muscle)
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Curare
competes w/ Ach for nicotinic receptor; decreases size of EPP, can cause death in maximal doses
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D-Tubocurarine
causes relaxation of skeletal muscle in anesthesia
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alpha-bungarotoxin
binds irreversibly to Ach receptors
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neostigmine
prevents degradation of Ach and prolongs action of Ach at motor end plate; AchE inhibitor
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hemicholinium
blocks choline reuptake and decreases Ach synthesis; skeletal muscle weakness
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dystrophin
actin binding protein to cytoskeleton/cell membrane
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titin
assoc w/ thick filaments; from M lines to Z disks; changes when sarcomere length changes
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nebulin
assoc w/ think filaments, sets length of thin filaments during assembly
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alpha actinin
anchors thin filament to Z disk
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calsequestrin
binds Ca in sarcoplasmic reticulum to decrease work required of SERCA
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inderol
blocks beta adrenergic receptors; decreases sympathetic responses (like anxiety)
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angiotensin
causes blood vessel constriction and increased BP
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vasopressin
increases peripheral resistance and BP
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viagra
inhib cGMP phosphodiesterase so more cGMP to increase blood flow to penis (normally NO binds to GC receptor to activate them and make cGMP)
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