physiology drugs

inhibits gastric H+ ATPase from transporting H into lumen of SI; ulcer Rx

block VG Na channels and prevent AP

block VG Na channels and prevent AP

blocks VG K channels, outward K current and repolarization

Ca channel blocker

Ca channel blocker

blocks Ach release from pre-synaptic terminal; paralysis of skeletal m and death from respiratory failure (diaphragm muscle)

competes w/ Ach for nicotinic receptor; decreases size of EPP, can cause death in maximal doses

causes relaxation of skeletal muscle in anesthesia

binds irreversibly to Ach receptors

prevents degradation of Ach and prolongs action of Ach at motor end plate; AchE inhibitor

blocks choline reuptake and decreases Ach synthesis; skeletal muscle weakness

actin binding protein to cytoskeleton/cell membrane

assoc w/ thick filaments; from M lines to Z disks; changes when sarcomere length changes

assoc w/ think filaments, sets length of thin filaments during assembly

anchors thin filament to Z disk

binds Ca in sarcoplasmic reticulum to decrease work required of SERCA

blocks beta adrenergic receptors; decreases sympathetic responses (like anxiety)

causes blood vessel constriction and increased BP

increases peripheral resistance and BP

inhib cGMP phosphodiesterase so more cGMP to increase blood flow to penis (normally NO binds to GC receptor to activate them and make cGMP)