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physiology drugs
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Omeprazole
inhibits gastric H+ ATPase from transporting H into lumen of SI; ulcer Rx
tetrodotoxin
block VG Na channels and prevent AP
lidocaine
block VG Na channels and prevent AP
TEA
blocks VG K channels, outward K current and repolarization
Nifedipine
Ca channel blocker
Verapamil
Ca channel blocker
Botulinis toxin
blocks Ach release from pre-synaptic terminal; paralysis of skeletal m and death from respiratory failure (diaphragm muscle)
Curare
competes w/ Ach for nicotinic receptor; decreases size of EPP, can cause death in maximal doses
D-Tubocurarine
causes relaxation of skeletal muscle in anesthesia
alpha-bungarotoxin
binds irreversibly to Ach receptors
neostigmine
prevents degradation of Ach and prolongs action of Ach at motor end plate; AchE inhibitor
hemicholinium
blocks choline reuptake and decreases Ach synthesis; skeletal muscle weakness
dystrophin
actin binding protein to cytoskeleton/cell membrane
titin
assoc w/ thick filaments; from M lines to Z disks; changes when sarcomere length changes
nebulin
assoc w/ think filaments, sets length of thin filaments during assembly
alpha actinin
anchors thin filament to Z disk
calsequestrin
binds Ca in sarcoplasmic reticulum to decrease work required of SERCA
inderol
blocks beta adrenergic receptors; decreases sympathetic responses (like anxiety)
angiotensin
causes blood vessel constriction and increased BP
vasopressin
increases peripheral resistance and BP
viagra
inhib cGMP phosphodiesterase so more cGMP to increase blood flow to penis (normally NO binds to GC receptor to activate them and make cGMP)
Author
embryo
ID
108713
Card Set
physiology drugs
Description
MS1/Mod 2: physiology, drugs
Updated
10/13/2011, 6:05:00 PM
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