Path fall midterm GI one

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Author:
jlolson83
ID:
108843
Filename:
Path fall midterm GI one
Updated:
2011-10-14 00:15:14
Tags:
GI Neoplasia Inflammation
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Description:
gi neoplasia
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  1. Mallory-Weiss tears

    from severe retching/vomiting

    GI bleed and hematemesis

    Rarely perforation
  2. Candida infection of esophagus
  3. HSV inclusions

    "eggs in a basket"

    infects esophagus, gu in immunocompromised people.
  4. CMV inclusion in esophageal infection
  5. GERD

    Hyperplasia of basal cells, mixed inflam cells, few eosinophils

    Dx endoscopically
  6. Eosinophilic esophagitis

    more in males

    dysphagia or food impaction (food sticks to esoph)
  7. Eosinophilic Esophagitis

    Trachealization of esophagus
  8. Barret's esophagus

    Glandular tissue creeps up esophagus

    Increased risk of cancer
  9. Barrett's esophagus

    bottom left is normal. top is dysplastic. hyperchromatic, stratified nuclei, little mucous production
  10. Barrett's esophagus

    High grade dysplagia
  11. Adenocarcinoma of the Esophagus (distal)

    M>F, caucasians>others
  12. Esophageal adenocarcinoma

    (epithelial/glandular)
  13. Esophageal squamous cell carcinoma

    • Very common world-wide
    • M>F
    • Inc risk with EtOH, tobacco, achalasia
  14. Esophageal squamous cell carcinoma

    • No glands
    • Basal, dark cell. Sometimes keratin forms.
  15. Normal fundic stomach

    V Pink parietal cells. Mucus cells
  16. Normal antrum stomach

    Lots of mucin glands
  17. Helicobacterial gastritis

    Curvilinear gram neg bacteria producing urease and toxin (CagA)
  18. H. Pylori gastritis

    Inflammatory cell infiltration
  19. Autoimmune gastritis

    Autoantibodies against parietal cells or intrinsic factor

    Causes hypochlorhydria and anemia
  20. Gastric polyp
  21. Gastric Polyp
  22. Gastric Polyp. Fundic gland polyp.
  23. Gastric adenoma. (Polyp)
  24. Localized/intestinal Gastric Carcinoma
  25. Diffuse infiltrating gastric carcinoma. More dangerous.
  26. Intestinal type Gastric Carcinoma.

    Gland formation
  27. Diffuse infiltrating gastric carcinoma

    Very differentiated. Signet ring cells all same, secrete mucin
  28. Intestinal lymphoma with serosal nodules
  29. GI lymphomas

    Diffuse thickening of small bowel
  30. GI lymphoma

    Gastric MALT lymphoma. Invastion of glands
  31. GI carcinoid tumor

    Ball like nests.

    • Look like carcinoma but less predictable behavior.
    • Neuroendocrine cell tumor.
  32. GI carcinoid tumor

    Neuroendocine secreting tumor

    monomorphic cells. glands don't secrete into duct, straight to blood. Membrane bound granules.
  33. GIST

    Gastrointestinal stromal tumor

    connective tissue mesenchyme tissue
  34. GIST

    Fleshy, firm tumor. Just bulges, no penetration.
  35. GIST

    Stains for C-kit or CD117
  36. Celiac disease

    Small intestine with villus atrophy. lots of lymphocyte infiltration.
  37. Diffuse eosinophilic infiltrates in parasitic infection. (Ascaris and Strongyloides)
  38. Schistosomiasis parasitic infection
  39. Entamoeba histolytica parasitic infection
    • Giardia lamblia
    • Parasitic enterocolitis
  40. Cryptosporidia parasitic infection

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