Physiological Chemistry

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Author:
lifesliaison
ID:
108887
Filename:
Physiological Chemistry
Updated:
2011-10-20 11:29:23
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physiological chemistry
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Description:
P.chem exam 4
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  1. CCK-PZ
    Intestinal hormone that targets the enzymes of the pancreas.
  2. What organ possess glycerol kinase activity (to any great extent)?
    Liver.
  3. Rate-limiting?
    CPT-1, CPT-2, CAT?
    CPT-1
  4. PLC
    Major bacterial toxin. Also associated physiologically with plasma membranes of animals. (PL à DAG + phosphoryl base (e.g., IP3)
  5. What is LCAT, and why do I need to know about it ?
    Lecithin:cholesterol acyltransferase (LCAT) is an integral enzyme associated with circulating high-density lipoprotein (HDL) particles, and it may also be found in hepatocytes. Circulating LCAT hydrolyzes an UFA from the 2-position of PLs in HDL, and passes that UFA on to CH as it enters the HDL particle from tissue cells. This accounts for the majority of circulating cholesterol esters (CEs). Note as well that the LCAT reaction is reversible.

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