Card Set Information
What antiacid causes constipation?Diarrhea?
Aluminum produces what S/E?
Magnesium produces what S/E?
loss of Deep Tendon Reflexes
How are the effects of constiption caused by Aluminum offset?
What Histamine receptor increases Gastric Acid secretion?
What Histamine receptor increases bronchial secretions and causes bronchoconstriction?
What 2nd generation H1 histamine blockers dont have sedating effects?
What H1 antagonist is used for motion sickness?
What H1 antagonist is an antianxiolytic?
1st generation of H1 blockers?
H2 blockers used for hypersecretion of gastric acid end in what??
What are the inhibitors of cyt p450?
HIV Protease inhibitors
What drugs produce gynecomastia?
What action decreases the effect of H2 receptor blockers?
Proton Pump inhibitors?
Triple Therapy for H.Pylori?
PPI decrease bioavailability of drugs that need acidity such as?
MOA of Sucralfate/Bismuth?
protective shield over ulcer allowing alkalinization to occur---heals ulcers
MOA of misoprositol?
PGE analog--inhibits gastric acid secretion
What drug is used when ulcers are caused by NSAIDS?
Centrally inhibiting Dopamine agonist in teh CTZ(chemotaxic zone)?
4 Dopamine blockers used as antiemetics?
Adverse reaction of the dopamine blockers used for antiemetics??
What drug blocks the labirynth-vestibular system as an antiemetic?
TO what family of drugs does it belong to?
What antihistamine is used for motion sickness?
What antihistamine drug is used for anxiety?
5HT3 BLOCKERS end in what?
2 5HT3 blcokers?
What is used as 1st line drug for chemotherapy induced nausea and vomiting?
Why are 5HT3 inhibitors used as first line drug for chemotherapy induced nausea and vomiting?
bc large amounts of 5HT result from chemotherapy killed cells which stimulate the CTZ center
What chemicals stimulate CTZ?
What chemicals stimulate the lateral and medial zones of the hypothalamus?
WHich drugs inhibit CTZ and GI emetic receptors?
Bc of the 5HT blocking action, what CNS symptom may occur?
note:sumatriptan--a 5HT agonist decreases vessel permeability and used for headache,...so it makes sense that if you block it , you get headache
Abdominal cramps and dry mouth may occur with what anti-emetic?
Dronabinol(Cannabinoid) is used for what 2 purposes?
Appetite stimulant in pts with anorexia and AIDS
activate receptors that block pain receptors in the GI
MOA of Aprepitant?
Substance P/Neurokinin receptor antagonist
What are the 2 emetic drugs?
MOA of activated Charcoal?
large surface area absorbs toxins
Activated charcoal is not used for which substance?
S/E of Activated Charcoal?
MOA of Ipecac?
stimulates DA receptors in CTZ
S/E of Ipecac?
MOA of Opiods?
opens K channels
closes Ca channels
Inhibits ach, NE, 5HT release
2 opiod Anti-diarrheals?
MOA of opiod anti-diarrheals?
bind to mu receptors and decrease myenteric activity
Diphenoxylate is given with what drug to prevent abuse?
In addition to treating peptic ulcers by providing a protective cover to allow for bicarbonate release and re-establishment fo pH, this drug is used as an anti-diarrheal?
Bulk forming laxative?
Polyethylene glycol and electrolyte is called?
Compound which increases luminal pressure?
Laxative used for bowel cleansing before colonoscopy?
Laxative used to decrease ammonia in patients with hepatic encephalopathy?
Why is castrol oil not used as a laxative?
bc of adverse effects
Anti-diarrheal for travelers diarrhea?
2 drugs with 5 asa for IBD?
Sulfasalazine is made up of what 2 chemicals?
sulfapyridine and 5-ASA
TNF blocker used for IBD?
2 TNF molecule antibodies?
Recombinant TNF receptor used to bind TNF in inflammatory condition?
5HT4 agonist for IBD?
What drug works on constipation in women with IBD?