Enterococci

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Author:
shutterbug81
ID:
108968
Filename:
Enterococci
Updated:
2011-10-14 19:39:43
Tags:
Case Study
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Description:
Case Study
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  1. Enterococci
    General Information
    • Colonic bacteria (commensal)
    • Facultative Anaerobes
    • Gamma Hemolytic (no clearing)
  2. Diseases of Enterococci
    • Endocarditis, UTI
    • Nosocomial infection
    • Persist on hands, surfaces, fecal aerosols
  3. Enterococci Virulence Factors
    • No potent toxin
    • Cytolysin
    • Ace adhisin- attach to collagen
    • fsr gene
  4. fsr gene of Enterococci
    • Encodes two proteases:
    • 1. gelatinase (GelE)
    • 2. Serine protease (SprE)
  5. Identification of Enterococci
    • Survive on 40% bile salts, 6.5% NaCl
    • Grow on bile esculin agar: metabolizes esculin to black medium (selective)
    • Resistant to optochin (used to differentiate from Streptococcus)
  6. Antibiotic Resistance of Enterococci
    • Vancomycin Resistance
    • Have multiple genes that modify pathway of peptidoglycan synthesis (horizontally transferred)
    • Treat with a combination of antibiotics

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