Unit 7 Lilley Chpt 38

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  1. having or pertaining to the ability to destroy or interfere with the development of a living organism. The term is used most commonly to refer to antibacterial drugs
  2. one of two types of tropical antimicrobial agent; a chemical that inhibits the growth and reproduction of microorganisms without necessarily killing them. It is also known as static agents
  3. antibiotics that kill bacteria
    Bactericidal Antibiotics
  4. Antibiotics that do not actually kill bacteria but rather inhibit their growth
    Bacteriostatic Antibiotics
  5. the designation for a broad, major class of antibiotics that includes four subclasses: penicillin, cephalosporins, carbapenems, and monobactams; so named because of the beta-lactam ring that is part of the chemical structure of all drugs in this class
  6. any of a group of enzymes produced by bacteria that catalyze the chemical opening of the crucial beta-lactam ring structures in beta-lactam antibiotics
  7. medications combined with certain penicillin drugs to block the effect of beta-lactamase enzymes
    Beta-lactamase inhibitors
  8. the establishment and growth of microorganisms on the skin, open wounds, or mucous membranes, or in secretions without causing adverse clinical signs or symptoms
  9. An infection that is acquired by persons who have not been hospitalized or had a medical procedure recently (within the past year)
    Community – Associated Infection
  10. The administration of antibiotics based on known results of culture and sensitivity testing identifying the pathogen causing infection
    Definitive Therapy
  11. one of two types of tropical antimicrobial agent; a chemical applied to nonliving objects to kill microorganisms. Also called cidal agents
  12. the administration of antibiotics based on practitioner’s judgment of the pathogens most likely to be causing an apparent infection; it involves the
    presumptive treatment of an infection to avoid treatment delay before specific culture information has been obtain
    Empiric Therapy
  13. An inheritied disorder in which the red blood
    cells are partially or complete deficient in glucose-6 phosphate dehydrogenase, a creitcal enzyme in the metabolism of glucose. Certain medications can cause hemolytic anemia in patients with this disorder. This is an example of a host factor related to drug therapy
    Glucose-6-Phosphate Dehydogenase (G6PD) deficiency
  14. An infection that is acquired during the course of receiving treatment for another condition in the health care facility. The infection is not present or incubating at the time of admission
    Healthcare Associated Infection
  15. Factors that are unique to the body of a particular patient that affect the patient’s susceptibility to infection and response to various antibiotic drugs
    Host Factors
  16. invasions and multiplications of microorganisms in body tissues
  17. Microscopic living organisms (also called microbes)
  18. Antibiotics taken before anticipated exposure to an
    infectious organism in an effort to prevent the development of infection
    Prophylactic Antibiotic Therapy
  19. A necrotizing inflammatory bowel condition that is often associated with antibiotic therapy. A more general term that is also used is antibiotic associated colitis
    Pseudomembranous Colitis
  20. A common genetic host factor in which the rate of metabolism of certain drugs is reduced
    Slow Acetylation
  21. referring to antibiotic treatment that is ineffective in treating a given infection. Possible causes include
    inappropriate drug therapy, insufficient drug dosing, and bacterial drug resistance
  22. (1) An infection occurring during antimicrobial treatment for another infection, resulting from overgrowth of an organism not susceptible to the
    antibiotic used.
    (2) A secondary microbial infection that occurs in addition to an earlier primary infection, often due to weakening of the patient’s immune system function by the first infection
  23. Substances that can interfere with normal prenatal development and cause one or more developmental abnormalities in the fetus
  24. Referring to antibiotic therapy that result in sufficient concentrations of the drug in the blood or other tissue to render it effective against specific bacterial pathogens
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Unit 7 Lilley Chpt 38
Unit 7 Lilley Chapter 38
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