Card Set Information
Psyc drugs final year exam
What type of drugs are haloperidol/chlorpromazine?
Typical/first generation antipsychotics
Use of haloperidol/chlorpromazine?
Common & serious side effects?
What advice would you give the patient?
1. schizophrenia, psychosis, delirium
2. sedation, tardive dyskinesia, anticholinergic effects.
NMS, cardiac (long QT)
3. Baseline ECG reqd. Avoid alcohol, careful when driving
What are antimuscarinic effects?
Dry mouth, constipation, blurred vision, dizziness
Name 3 atypical antipsychotics?
Quetiapine, Olanzapine, Clozapine
Common & serious SEs of atypical antipsychotics?
: sedation, weight gain, [antimusc]
dry mouth, constipation, blurred vision
: DM/DKA, NMS causing high fever, heart, kidney probs
Clozapine --> clozapenia (neutropinia)
What is respiridone?
Atypical antipsychotic, "watered down haloperidol" (maintains some dyskinesia)
Name 3 benzodiazepines?
Diazepam, lorazepam, clozapam
What are benzos used for?
short term for anxiety, insomnia also seizures, alcohol withdrawal
Common & serious SEs of benzos?
: sedation/drowsy, can muddle
thinking, mess with memory
: cause dependence, decrease breathing
Name 3 SSRIs
Fluoxetine, Paroxetine, Citalopram
Common & serious side effects of SSRIs?
Common – FINISH (fat, insomnia, nausea,
irrit/anxiety, sex func dec, headaches)
Serious – initial inc in suicidal thoughs
What advice would you give pt starting SSRIs?
4-6 wks for people to notice effect
Initial increase in anxiety/suicide thoughts so need follow up after 1-2 wks.
Will need to be on it for 6 months after feeling better (2-3y if recurrent)
What are amitryptiline & nortryptiline & how does it work?
seratonin & NA reuptake inhibition
Has effects on histamine receptor, a receptor and anticholinergic
Common & serious SEs of TCAs?
Common – [antichol] dry mouth, blurred vision, constipation, sedation [antihist], hT, dizzy [a recep], weight gain
Serious – seizures, coma, arrythmias
Order of prescribing antidepressants?
2. (try diff SSRI)
What is venlafaxine?
SNRI (seratonin, noradrealine reuptake inhib)
What might a patient switch to SNRIs from TCAs?
Less sedative & antimuscarinic effects
Common & serious SEs of venlafaxine?
: rash, [HTN] which if sustained has effects on your body, headaches, tummy upset
: Heart effects if stopped suddenly
Example of a MAOI & major SE?
Hypertensive crisis - special diet required
What is lithium & what is it used for?
Common & serious SEs of Lithium?
Common = 4T’s
: tremor, terrible kidney (pee lots),
tummy upset, thyroid inc
Serious – teratogenic, kidney and heart arrythmias, seizures, coma if too much
What is lamotragine?
Common/serious - cerebellar sx, blood dx (bleeding, infection)
What are sodium valproate/Carbamazepine? When are they used in psychiartry?
Used as mood stabilisers when unresponsive/can't use Li
Common & serious SEs of sodium valproate/carbamazepine?
: Sedation, headache, cerebellar
: Blood dx (bleeding, infec)
(NaVal) – teratogen
(Carba) – Increase suicidal thoughts