Path T3 cancers signals.txt

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Author:
kepling
ID:
110007
Filename:
Path T3 cancers signals.txt
Updated:
2011-10-18 22:10:57
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Path T3 cancers signals
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Description:
Path T3 cancers signals
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  1. SIS
    • Growth Factor
    • - Astrocytoma, gliocytoma/blastoma
  2. HST
    • GF
    • Karposi Sarcoma
  3. EGFR (ERB B1)
    • SIS Receptor
    • Head, Neck, Lung carcinoma
  4. Her2Neu (ERB B2)
    • HST receptor
    • Breast Carcinoma
  5. TGF-Beta
    • Receptor
    • Colon & Pancreatic cancer
  6. VHL
    • Suppressor
    • -Von-hippel lindau disease
    • -clear cell renal carcinoma
    • -cavernous hemangioma
  7. Cadherin
    • adherance factor
    • Breast & Visceral cancer
  8. PTEN
    • PI3 pathway
    • Endometrial carcinoma
  9. RAS
    • Transducer
    • Adenocarcinoma (colon & Pancreas)
  10. NF-1
    • Transducer
    • Neurofibromatosis
  11. ABL
    • Transducer
    • CML
  12. APC/Beta-catenin
    • Familal Adenomatous polyposus
    • Colon adenomatous carcinoma
  13. BCL-2
    • Adhesion evader
    • B-cell follicular lymphoma
  14. MYC
    • Transcription
    • Burkitt's lymphoma
  15. N-MYC
    • Transcription
    • Neuroblastoma
  16. INK-4
    • Transcription inhibitor
    • Familial melanoma & HPV
  17. RB
    • Transcription
    • Retinoblastoma, Osteosarcoma, HPV
  18. NER
    • Transcription
    • Xeroderma pigmentosa
  19. Mismatch repair (MLH,MSH)
    hereditary Non-polyp colon cancer (HNPCC)
  20. BRCA-1&2
    • Transcription
    • Breast & Ovarian cancer
  21. ATM
    • Transcription
    • Ataxia telangiectasia
  22. P53
    • Transcription
    • **All cancers
    • Li Fraumeni familial cancer
  23. Cyclin D/CDK-4
    • breast cancer
    • glioblastoma
    • melanoma
  24. BRAF
    Melanoma

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