Paraneoplastic syndromes

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  1. Acanthosis nigricans
    Black, verrucoid-appearing lesion

    Stomach carcinoma
  2. Eaton-Lambert syndrome
    Myasthenia gravis-like sx (m weakness)

    Small cell carcinoma of lung
  3. Hypertrophic osteoarthropathy
    Periosteal rxn of distal phalanx

    Bronchogenic carcinoma
  4. Nonbacterial thrombotic endocarditis
    Sterile vegetations on mitral valve

    Mucus-secreting pancreatic and colorectal carcinomas
  5. Seborrheic keratosis
    Sudden numerous pigmented seborrheic keratoses (Leser-Trelat sign)

    Stomach carcinoma
  6. Superficial migratory thrombophlebitis
    Relsease of procoagulants (Trousseaus's sign)

    Pancreatic carcinoma
  7. Nephrotic syndrome
    Diffuse membranous glomerulopathy

    Lung, breast, stomach carcinomas
  8. Cushing Syndrome
    ACTH

    • Small cell carcinoma of lung
    • Medullary Carcinoma of thyroid
  9. Gynecomastia
    hCG

    Choriocarcinoma
  10. Hypercalcemia
    • PTH-related protein
    • Calcitriol

    • Renal cell carcinoma
    • Primary squamous cell carcinoma of lung
    • Breast Carcinoma
    • Malignant lymphomas
  11. Hypoglycemia
    Insulin-like factor

    Hepatocellular carcinoma
  12. Hypernatremia
    ADH

    Small cell carcinoma of lung
  13. Secondary polycythemia
    Epo

    Renal cell and hepatocellular carcinoma
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ID
110173
Card Set
Paraneoplastic syndromes
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